Category Archives: BigBang

BigBang

Cosmic portrait

Make a note in your calendar if you are so inclined: you’ll be photographed from space on July 19, 2013, sometime between 9.27 and 9.42 pm (GMT).

No, this is not another wacky mapping stunt courtesy of Google. Rather, NASA’s Cassini spacecraft, which will be somewhere in the vicinity of Saturn, will train its cameras on us for a global family portrait.

From NASA:

NASA’s Cassini spacecraft, now exploring Saturn, will take a picture of our home planet from a distance of hundreds of millions of miles on July 19. NASA is inviting the public to help acknowledge the historic interplanetary portrait as it is being taken.

Earth will appear as a small, pale blue dot between the rings of Saturn in the image, which will be part of a mosaic, or multi-image portrait, of the Saturn system Cassini is composing.

“While Earth will be only about a pixel in size from Cassini’s vantage point 898 million [1.44 billion kilometers] away, the team is looking forward to giving the world a chance to see what their home looks like from Saturn,” said Linda Spilker, Cassini project scientist at NASA’s Jet Propulsion Laboratory in Pasadena, Calif. “We hope you’ll join us in waving at Saturn from Earth, so we can commemorate this special opportunity.”

Cassini will start obtaining the Earth part of the mosaic at 2:27 p.m. PDT (5:27 p.m. EDT or 21:27 UTC) and end about 15 minutes later, all while Saturn is eclipsing the sun from Cassini’s point of view. The spacecraft’s unique vantage point in Saturn’s shadow will provide a special scientific opportunity to look at the planet’s rings. At the time of the photo, North America and part of the Atlantic Ocean will be in sunlight.

Unlike two previous Cassini eclipse mosaics of the Saturn system in 2006, which captured Earth, and another in 2012, the July 19 image will be the first to capture the Saturn system with Earth in natural color, as human eyes would see it. It also will be the first to capture Earth and its moon with Cassini’s highest-resolution camera. The probe’s position will allow it to turn its cameras in the direction of the sun, where Earth will be, without damaging the spacecraft’s sensitive detectors.

“Ever since we caught sight of the Earth among the rings of Saturn in September 2006 in a mosaic that has become one of Cassini’s most beloved images, I have wanted to do it all over again, only better,” said Carolyn Porco, Cassini imaging team lead at the Space Science Institute in Boulder, Colo. “This time, I wanted to turn the entire event into an opportunity for everyone around the globe to savor the uniqueness of our planet and the preciousness of the life on it.”

Porco and her imaging team associates examined Cassini’s planned flight path for the remainder of its Saturn mission in search of a time when Earth would not be obstructed by Saturn or its rings. Working with other Cassini team members, they found the July 19 opportunity would permit the spacecraft to spend time in Saturn’s shadow to duplicate the views from earlier in the mission to collect both visible and infrared imagery of the planet and its ring system.

“Looking back towards the sun through the rings highlights the tiniest of ring particles, whose width is comparable to the thickness of hair and which are difficult to see from ground-based telescopes,” said Matt Hedman, a Cassini science team member based at Cornell University in Ithaca, N.Y., and a member of the rings working group. “We’re particularly interested in seeing the structures within Saturn’s dusty E ring, which is sculpted by the activity of the geysers on the moon Enceladus, Saturn’s magnetic field and even solar radiation pressure.”

This latest image will continue a NASA legacy of space-based images of our fragile home, including the 1968 “Earthrise” image taken by the Apollo 8 moon mission from about 240,000 miles (380,000 kilometers) away and the 1990 “Pale Blue Dot” image taken by Voyager 1 from about 4 billion miles (6 billion kilometers) away.

Read the entire article here.

Image: This simulated view from NASA’s Cassini spacecraft shows the expected positions of Saturn and Earth on July 19, 2013, around the time Cassini will take Earth’s picture. Cassini will be about 898 million miles (1.44 billion kilometers) away from Earth at the time. That distance is nearly 10 times the distance from the sun to Earth. Courtesy: NASA/JPL-Caltech

BigBang, Literature

Asteroid 5099

Iain (M.) Banks is now where he rightfully belongs — hurtling through space. Though, we fear that he may well not be traveling as fast as he would have wished.

From the Minor Planet Center:

In early April of this year we learnt from Iain Banks himself that he was sick, very sick. Cancer that started in the gall bladder spread quickly and precluded any cure, though he still hoped to be around for a while and see his upcoming novel, The Quarry, hit store shelves in late June. He never did—Iain Banks died on June 9th.

I was introduced to Iain M. Banks’s Sci-Fi novels in graduate school by a good friend who also enjoyed Sci-Fi; he couldn’t believe I’d never even heard of him and remedied what he saw as a huge lapse in my Sci-Fi culture by lending me a couple of his novels. After that I read a few more novels of my own volition because Mr Banks truly was a gifted story teller.

When I heard of his sickness I immediately asked myself what I could do for Mr Banks, and the answer was obvious: Give him an asteroid!

The Minor Planet Center only has the authority to designate new asteroid discoveries (e.g., ’1971 TD1?) and assign numbers to those whose orbits are of a high enough accuracy (e.g., ’5099?), but names for numbered asteroids must be submitted to, and approved by, the Committee for Small Body Nomenclature (CSBN) of the IAU (International Astronomical Union). With the help of Dr Gareth Williams, the MPC’s representative on the CSBN, we submitted a request to name an asteroid after Iain Banks with the hope that it would be approved soon enough for Mr Banks to enjoy it. Sadly, that has not been possible. Nevertheless, I am here to announce that on June 23rd, 2013, asteroid (5099) was officially named Iainbanks by the IAU, and will be referred to as such for as long as Earth Culture may endure.

The official citation for the asteroid reads:

Iain M. Banks (1954-2013) was a Scottish writer best known for the Culture series of science ?ction novels; he also wrote ?ction as Iain Banks. An evangelical atheist and lover of whisky, he scorned social media and enjoyed writing music. He was an extra in Monty Python & The Holy Grail.

Asteroid Iainbanks resides in the Main Asteroid Belt of the Sol system; with a size of 6.1 km (3.8 miles), it takes 3.94 years to complete a revolution around the Sun. It is most likely of a stony composition. Here is an interactive 3D orbit diagram.

The Culture is an advanced society in whose midst most of Mr Banks’s Sci-Fi novels take place. Thanks to their technology they are able to hollow out asteroids and use them as ships capable of faster-than-light travel while providing a living habitat with centrifugally-generated gravity for their thousands of denizens. I’d like to think Mr Banks would have been amused to have his own rock.

Read the entire article here.

Image: Orbit Diagram of asteroid (5099) Iainbanks. Cyan ellipses represent the orbits of the planets (from closer to further from the Sun) Mercury, Venus, Earth, Mars and Jupiter. The black ellipse represents the orbit of asteroid Iainbanks. The shaded region lies below the ecliptic plane, the non shaded, above. Courtesy of Minor Planet Center.

BigBang

Impossible Chemistry in Space

Combine the vastness of the universe with the probabilistic behavior of quantum mechanics and you get some rather odd chemical results. This includes the spontaneous creation of some complex organic molecules in interstellar space — previously believed to be far too inhospitable for all but the lowliest forms of matter.

From the New Scientist:

Quantum weirdness can generate a molecule in space that shouldn’t exist by the classic rules of chemistry. If interstellar space is really a kind of quantum chemistry lab, that might also account for a host of other organic molecules glimpsed in space.

Interstellar space should be too cold for most chemical reactions to occur, as the low temperature makes it tough for molecules drifting through space to acquire the energy needed to break their bonds. “There is a standard law that says as you lower the temperature, the rates of reactions should slow down,” says Dwayne Heard of the University of Leeds, UK.

Yet we know there are a host of complex organic molecules in space. Some reactions could occur when different molecules stick to the surface of cosmic dust grain. This might give them enough time together to acquire the energy needed to react, which doesn’t happen when molecules drift past each other in space.

Not all reactions can be explained in this way, though. Last year astronomers discovered methoxy molecules – containing carbon, hydrogen and oxygen – in the Perseus molecular cloud, around 600 light years from Earth. But researchers couldn’t produce this molecule in the lab by allowing reactants to condense on dust grains, leaving a puzzle as to how it could have formed.

Molecular hang-out

Another route to methoxy is to combine a hydroxyl radical and methanol gas, both present in space. But this reaction requires hurdling a significant energy barrier – and the energy to do that simply isn’t available in the cold expanse of space.

Heard and his colleagues wondered if the answer lay in quantum mechanics: a process called quantum tunnelling might give the hydroxyl radical a small chance to cheat by digging through the barrier instead of going over it, they reasoned.

So, in another attempt to replicate the production of methoxy in space, the team chilled gaseous hydroxyl and methanol to 63 kelvin – and were able to produce methoxy.

The idea is that at low temperatures, the molecules slow down, increasing the likelihood of tunnelling. “At normal temperatures they just collide off each other, but when you go down in temperature they hang out together long enough,” says Heard.

Impossible chemistry

The team also found that the reaction occurred 50 times faster via quantum tunnelling than if it occurred normally at room temperature by hurdling the energy barrier. Empty space is much colder than 63 kelvin, but dust clouds near stars can reach this temperature, adds Heard.

“We’re showing there is organic chemistry in space of the type of reactions where it was assumed these just wouldn’t happen,” says Heard.

That means the chemistry of space may be richer than we had imagined. “There is maybe a suite of chemical reactions we hadn’t yet considered occurring in interstellar space,” agrees Helen Fraser of the University of Strathclyde, UK, who was not part of the team.

Read the entire article here.

Image: Amino-1-methoxy-4-methylbenzol, featuring methoxy molecular structure, recently found in interstellar space. Courtesy of Wikipedia.

BigBang

Building a Liver

In yet another breakthrough for medical science, researchers have succeeded in growing a prototypical human liver in the lab.

From the New York Times:

Researchers in Japan have used human stem cells to create tiny human livers like those that arise early in fetal life. When the scientists transplanted the rudimentary livers into mice, the little organs grew, made human liver proteins, and metabolized drugs as human livers do.

They and others caution that these are early days and this is still very much basic research. The liver buds, as they are called, did not turn into complete livers, and the method would have to be scaled up enormously to make enough replacement liver buds to treat a patient. Even then, the investigators say, they expect to replace only 30 percent of a patient’s liver. What they are making is more like a patch than a full liver.

But the promise, in a field that has seen a great deal of dashed hopes, is immense, medical experts said.

“This is a major breakthrough of monumental significance,” said Dr. Hillel Tobias, director of transplantation at the New York University School of Medicine. Dr. Tobias is chairman of the American Liver Foundation’s national medical advisory committee.

“Very impressive,” said Eric Lagasse of the University of Pittsburgh, who studies cell transplantation and liver disease. “It’s novel and very exciting.”

The study was published on Wednesday in the journal Nature.

Although human studies are years away, said Dr. Leonard Zon, director of the stem cell research program at Boston Children’s Hospital, this, to his knowledge, is the first time anyone has used human stem cells, created from human skin cells, to make a functioning solid organ, like a liver, as opposed to bone marrow, a jellylike organ.

Ever since they discovered how to get human stem cells — first from embryos and now, more often, from skin cells — researchers have dreamed of using the cells for replacement tissues and organs. The stem cells can turn into any type of human cell, and so it seemed logical to simply turn them into liver cells, for example, and add them to livers to fill in dead or damaged areas.

But those studies did not succeed. Liver cells did not take up residence in the liver; they did not develop blood supplies or signaling systems. They were not a cure for disease.

Other researchers tried making livers or other organs by growing cells on scaffolds. But that did not work well either. Cells would fall off the scaffolds and die, and the result was never a functioning solid organ.

Researchers have made specialized human cells in petri dishes, but not three-dimensional structures, like a liver.

The investigators, led by Dr. Takanori Takebe of the Yokohama City University Graduate School of Medicine, began with human skin cells, turning them into stem cells. By adding various stimulators and drivers of cell growth, they then turned the stem cells into human liver cells and began trying to make replacement livers.

They say they stumbled upon their solution. When they grew the human liver cells in petri dishes along with blood vessel cells from human umbilical cords and human connective tissue, that mix of cells, to their surprise, spontaneously assembled itself into three-dimensional liver buds, resembling the liver at about five or six weeks of gestation in humans.

Then the researchers transplanted the liver buds into mice, putting them in two places: on the brain and into the abdomen. The brain site allowed them to watch the buds grow. The investigators covered the hole in each animal’s skull with transparent plastic, giving them a direct view of the developing liver buds. The buds grew and developed blood supplies, attaching themselves to the blood vessels of the mice.

The abdominal site allowed them to put more buds in — 12 buds in each of two places in the abdomen, compared with one bud in the brain — which let the investigators ask if the liver buds were functioning like human livers.

They were. They made human liver proteins and also metabolized drugs that human livers — but not mouse livers — metabolize.

The approach makes sense, said Kenneth Zaret, a professor of cellular and developmental biology at the University of Pennsylvania. His research helped establish that blood and connective tissue cells promote dramatic liver growth early in development and help livers establish their own blood supply. On their own, without those other types of cells, liver cells do not develop or form organs.

Read the entire article here.

Image: Diagram of the human liver. Courtesy of Encyclopedia Britannica.

BigBang

Everywhere And Nowhere

Most physicists believe that dark matter exists, but have never seen it, only deduced its existence. This is a rather unsettling state of affairs since by most estimates dark matter (and possibly dark energy) accounts for 95 percent of the universe. The stuff we are made from, interact with and see on a daily basis — atoms, their constituents and their forces — is a mere 5 percent.

From the Atlantic:

Here’s a little experiment.

Hold up your hand.

Now put it back down.

In that window of time, your hand somehow interacted with dark matter — the mysterious stuff that comprises the vast majority of the universe. “Our best guess,” according to Dan Hooper, an astronomy professor at the University of Chicago and a theoretical astrophysicist at the Fermi National Accelerator Laboratory, “is that a million particles of dark matter passed through your hand just now.”

Dark matter, in other words, is not merely the stuff of black holes and deep space. It is all around us. Somehow. We’re pretty sure.

But if you did the experiment — as the audience at Hooper’s talk on dark matter and other cosmic mysteries did at the Aspen Ideas Festival today — you didn’t feel those million particles. We humans have no sense of their existence, Hooper said, in part because they don’t hew to the forces that regulate our movement in the world — gravity, electromagnetism, the forces we can, in some way, feel. Dark matter, instead, is “this ghostly, elusive stuff that dominates our universe,” Hooper said.

It’s everywhere. And it’s also, as far as human knowledge is concerned, nowhere.

And yet, despite its mysteries, we know it’s out there. “All astronomers are in complete conviction that there is dark matter,” said Richard Massey, the lead author of a recent study mapping the dark matter of the universe, and Hooper’s co-panelist. The evidence for its existence, Hooper agreed, is “overwhelming.” And yet it’s evidence based on deduction: through our examinations of the observable universe, we make assumptions about the unobservable version.

Dark matter, in other words, is aptly named. A full 95 percent of the universe — the dark matter, the stuff that both is and is not — is effectively unknown to us. “All the science that we’ve ever done only ever examines five percent of the universe,” Massey said. Which means that there are still mysteries to be unraveled, and dark truths to be brought to light.

And it also means, Massey pointed out, that for scientists, “the job security is great.”

You might be wondering, though: given how little we know about dark matter, how is it that Hooper knew that a million particles of the stuff passed through your hand as you raised and lowered it?

“I cheated a little,” Hooper admitted. He assumed a particular mass for the individual particles. “We know what the density of dark matter is on Earth from watching how the Milky Way rotates. And we know roughly how fast they’re going. So you take those two bits of information, and all you need to know is how much mass each individual particle has, and then I can get the million number. And I assumed a kind of traditional guess. But it could be 10,000 higher; it could be 10,000 lower.”

Read the entire article here.

BigBang, Environs

Circadian Rhythm in Vegetables

The vegetables you eat may be better for you based on how and when they are exposed to light. Just as animals adhere to circadian rhythms, research shows that some plants may generate different levels of healthy nutritional metabolites based the light cycle as well.

From ars technica:

When you buy vegetables at the grocery store, they are usually still alive. When you lock your cabbage and carrots in the dark recess of the refrigerator vegetable drawer, they are still alive. They continue to metabolize while we wait to cook them.

Why should we care? Well, plants that are alive adjust to the conditions surrounding them. Researchers at Rice University have shown that some plants have circadian rhythms, adjusting their production of certain chemicals based on their exposure to light and dark cycles. Understanding and exploiting these rhythms could help us maximize the nutritional value of the vegetables we eat.

According to Janet Braam, a professor of biochemistry at Rice, her team’s initial research looked at how Arabidopsis, a common plant model for scientists, responded to light cycles. “It adjusts its defense hormones before the time of day when insects attack,” Braam said. Arabidopsis is in the same plant family as the cruciforous vegetables—broccoli, cabbage, and kale—so Braam and her colleagues decided to look for a similar light response in our foods.

They bought some grocery store cabbage and brought it back to the lab so they could subject the cabbage to the same tests they gave their model plant, which involved offering up living, leafy vegetables to a horde of hungry caterpillars. First, half the cabbages were exposed to a normal light and dark cycle, the same schedule as the caterpillars, while the other half were exposed to the opposite light cycle.

The caterpillars tend to feed in the late afternoon, according to Braam, so the light signals the plants to increase production of glucosinolates, a chemical that the insects don’t like. The study found that cabbages that adjusted to the normal light cycle had far less insect damage than the jet-lagged cabbages.

While it’s cool to know that cabbages are still metabolizing away and responding to light stimulus days after harvest, Braam said that this process could affect the nutritional value of the cabbage. “We eat cabbage, in part, because these glucosinolates are anti-cancer compounds,” Braam said.

Glucosinolates are only found in the cruciform vegetable family, but the Rice team wanted to see if other vegetables demonstrated similar circadian rhythms. They tested spinach, lettuce, zucchini, blueberries, carrots, and sweet potatoes. “Luckily, our caterpillar isn’t picky,” Braam said. “It’ll eat just about anything.”

Just like with the cabbage, the caterpillars ate far less of the vegetables trained on the normal light schedule. Even the fruits and roots increased production of some kind of anti-insect compound in response to light stimulus.

Metabolites affected by circadian rhythms could include vitamins and antioxidants. The Rice team is planning follow-up research to begin exploring how the cycling phenomenon affects known nutrients and if the magnitude of the shifts are large enough to have an impact on our diets. “We’ve uncovered some very basic stimuli, but we haven’t yet figured out how to amplify that for human nutrition,” Braam said.

Read the entire article here.

BigBang

The Mother of All Storms

Some regions of our planet are home to violent and destructive storms. However, one look at a recent mega-storm on Saturn may put it all in perspective — it could be much, much worse.

From ars technica:

Jupiter’s Great Red Spot may get most of the attention, but it’s hardly the only big weather event in the Solar System. Saturn, for example, has an odd hexagonal pattern in the clouds at its north pole, and when the planet tilted enough to illuminate it, the light revealed a giant hurricane embedded in the center of the hexagon. Scientists think the immense storm may have been there for years.

But Saturn is also home to transient storms that show up sporadically. The most notable of these are the Great White Spots, which can persist for months and alter the weather on a planetary scale. Great White Spots are rare, with only six having been observed since 1876. When one formed in 2010, we were lucky enough to have the Cassini orbiter in place to watch it from close up. Even though the head of the storm was roughly 7,000 km across, Cassini’s cameras were able to image it at resolutions where each pixel was only 14 km across, allowing an unprecedented view into the storm’s dynamics.

The storm turned out to be very violent, with convective features as big as 3,000 km across that could form and dissipate in as little as 10 hours. Winds of over 400 km/hour were detected, and the pressure gradient between the storm and the unaffected areas nearby was twice that of the one observed in the Great Red Spot of Jupiter. By carefully mapping the direction of the winds, the authors were able to conclude that the head of the White Spot was an anti-cyclone, with winds orbiting around a central feature.

Convection that brings warm material up from the depths of Saturn’s atmosphere appears to be key to driving these storms. The authors built an atmospheric model that could reproduce the White Spot and found that shutting down the energy injection from the lower atmosphere was enough to kill the storm. In addition, observations suggest that many areas of the storm contain freshly condensed particles, which may represent material that was brought up from the lower atmosphere and then condensed when it reached the cooler upper layers.

The Great White spot was an anticyclone, and the authors’ model suggests that there’s only a very narrow band of winds on Saturn that enable the formation of a Great White Spot. The convective activity won’t trigger a White Spot anywhere outside the range of 31.5° and 32.4°N, which probably goes a long way toward explaining why the storms are so rare.

Read the entire article here.

Image: The huge storm churning through the atmosphere in Saturn’s northern hemisphere overtakes itself as it encircles the planet in this true-color view from NASA’s Cassini spacecraft. Courtesy of NASA/JPL.

BigBang

What Makes Us Human

Psychologist Jerome Kagan leaves no stone unturned in his quest to determine what makes us distinctly human. His latest book, The Human Spark: The science of human development, comes up with some fresh conclusions.

From the New Scientist:

What is it that makes humans special, that sets our species apart from all others? It must be something connected with intelligence – but what exactly? People have asked these questions for as long as we can remember. Yet the more we understand the minds of other animals, the more elusive the answers to these questions have become.

The latest person to take up the challenge is Jerome Kagan, a former professor at Harvard University. And not content with pinning down the “human spark” in the title of his new book, he then tries to explain what makes each of us unique.

As a pioneer in the science of developmental psychology, Kagan has an interesting angle. A life spent investigating how a fertilised egg develops into an adult human being provides him with a rich understanding of the mind and how it differs from that of our closest animal cousins.

Human and chimpanzee infants behave in remarkably similar ways for the first four to six months, Kagan notes. It is only during the second year of life that we begin to diverge profoundly. As the toddler’s frontal lobes expand and the connections between the brain sites increase, the human starts to develop the talents that set our species apart. These include “the ability to speak a symbolic language, infer the thoughts and feelings of others, understand the meaning of a prohibited action, and become conscious of their own feelings, intentions and actions”.

Becoming human, as Kagan describes it, is a complex dance of neurobiological changes and psychological advances. All newborns possess the potential to develop the universal human properties “inherent in their genomes”. What makes each of us individual is the unique backdrop of genetics, epigenetics, and the environment against which this development plays out.

Kagan’s research highlighted the role of temperament, which he notes is underpinned by at least 1500 genes, affording huge individual variation. This variation, in turn, influences the way we respond to environmental factors including family, social class, culture and historical era.

But what of that human spark? Kagan seems to locate it in a quartet of qualities: language, consciousness, inference and, especially, morality. This is where things start to get weird. He would like you to believe that morality is uniquely human, which, of course, bolsters his argument. Unfortunately, it also means he has to deny that a rudimentary morality has evolved in other social animals whose survival also depends on cooperation.

Instead, Kagan argues that morality is a distinctive property of our species, just as “fish do not have lungs”. No mention of evolution. So why are we moral, then? “The unique biology of the human brain motivates children and adults to act in ways that will allow them to arrive at the judgement that they are a good person.” That’s it?

Warming to his theme, Kagan argues that in today’s world, where traditional moral standards have been eroded and replaced by a belief in the value of wealth and celebrity, it is increasingly difficult to see oneself as a good person. He thinks this mismatch between our moral imperative and Western culture helps explain the “modern epidemic” of mental illness. Unwittingly, we have created an environment in which the human spark is fading.

Some of Kagan’s ideas are even more outlandish, surely none more so than the assertion that a declining interest in natural sciences may be a consequence of mothers becoming less sexually mysterious than they once were. More worryingly, he doesn’t seem to believe that humans are subject to the same forces of evolution as other animals.

Read the entire article here.

BigBang, tD, Technica

Law, Common Sense and Your DNA

Paradoxically the law and common sense often seem to be at odds. Justice may still be blind, at least in most open democracies, but there seems to be no question as to the stupidity of much of our law.

Some examples: in Missouri it’s illegal to drive with an uncaged bear in the car; in Maine, it’s illegal to keep Christmas decorations up after January 14th; in New Jersey, it’s illegal to wear a bulletproof vest while committing murder; in Connecticut, a pickle is not an official, legal pickle unless it can bounce; in Louisiana, you can be fined $500 for instructing a pizza delivery service to deliver pizza to a friend unknowingly.

So, today we celebrate a victory for common sense and justice over thoroughly ill-conceived and badly written law — the U.S. Supreme Court unanimously struck down laws granting patents to corporations for human genes.

Unfortunately though, due to the extremely high financial stakes this is not likely to be the last we hear about big business seeking to patent or control the building blocks to life.

From the WSJ:

The Supreme Court unanimously ruled Thursday that human genes isolated from the body can’t be patented, a victory for doctors and patients who argued that such patents interfere with scientific research and the practice of medicine.

The court was handing down one of its most significant rulings in the age of molecular medicine, deciding who may own the fundamental building blocks of life.

The case involved Myriad Genetics Inc., which holds patents related to two genes, known as BRCA1 and BRCA2, that can indicate whether a woman has a heightened risk of developing breast cancer or ovarian cancer.

Justice Clarence Thomas, writing for the court, said the genes Myriad isolated are products of nature, which aren’t eligible for patents.

“Myriad did not create anything,” Justice Thomas wrote in an 18-page opinion. “To be sure, it found an important and useful gene, but separating that gene from its surrounding genetic material is not an act of invention.”

Even if a discovery is brilliant or groundbreaking, that doesn’t necessarily mean it’s patentable, the court said.

However, the ruling wasn’t a complete loss for Myriad. The court said that DNA molecules synthesized in a laboratory were eligible for patent protection. Myriad’s shares soared after the court’s ruling.

The court adopted the position advanced by the Obama administration, which argued that isolated forms of naturally occurring DNA weren’t patentable, but artificial DNA molecules were.

Myriad also has patent claims on artificial genes, known as cDNA.

The high court’s ruling was a win for a coalition of cancer patients, medical groups and geneticists who filed a lawsuit in 2009 challenging Myriad’s patents. Thanks to those patents, the Salt Lake City company has been the exclusive U.S. commercial provider of genetic tests for breast cancer and ovarian cancer.

“Today, the court struck down a major barrier to patient care and medical innovation,” said Sandra Park of the American Civil Liberties Union, which represented the groups challenging the patents. “Because of this ruling, patients will have greater access to genetic testing and scientists can engage in research on these genes without fear of being sued.”

Myriad didn’t immediately respond to a request for comment.

The challengers argued the patents have allowed Myriad to dictate the type and terms of genetic screening available for the diseases, while also dissuading research by other laboratories.

Read the entire article here.

Image: Gene showing the coding region in a segment of eukaryotic DNA. Courtesy of Wikipedia.

BigBang

Dead Man Talking

Graham is a man very much alive. But, his mind has convinced him that his brain is dead and that he killed it.

From the New Scientist:

Name: Graham
Condition: Cotard’s syndrome

“When I was in hospital I kept on telling them that the tablets weren’t going to do me any good ’cause my brain was dead. I lost my sense of smell and taste. I didn’t need to eat, or speak, or do anything. I ended up spending time in the graveyard because that was the closest I could get to death.”

Nine years ago, Graham woke up and discovered he was dead.

He was in the grip of Cotard’s syndrome. People with this rare condition believe that they, or parts of their body, no longer exist.

For Graham, it was his brain that was dead, and he believed that he had killed it. Suffering from severe depression, he had tried to commit suicide by taking an electrical appliance with him into the bath.

Eight months later, he told his doctor his brain had died or was, at best, missing. “It’s really hard to explain,” he says. “I just felt like my brain didn’t exist any more. I kept on telling the doctors that the tablets weren’t going to do me any good because I didn’t have a brain. I’d fried it in the bath.”

Doctors found trying to rationalise with Graham was impossible. Even as he sat there talking, breathing – living – he could not accept that his brain was alive. “I just got annoyed. I didn’t know how I could speak or do anything with no brain, but as far as I was concerned I hadn’t got one.”

Baffled, they eventually put him in touch with neurologists Adam Zeman at the University of Exeter, UK, and Steven Laureys at the University of Liège in Belgium.

“It’s the first and only time my secretary has said to me: ‘It’s really important for you to come and speak to this patient because he’s telling me he’s dead,'” says Laureys.

Limbo state

“He was a really unusual patient,” says Zeman. Graham’s belief “was a metaphor for how he felt about the world – his experiences no longer moved him. He felt he was in a limbo state caught between life and death”.

No one knows how common Cotard’s syndrome may be. A study published in 1995 of 349 elderly psychiatric patients in Hong Kong found two with symptoms resembling Cotard’s (General Hospital Psychiatry, DOI: 10.1016/0163-8343(94)00066-M). But with successful and quick treatments for mental states such as depression – the condition from which Cotard’s appears to arise most often – readily available, researchers suspect the syndrome is exceptionally rare today. Most academic work on the syndrome is limited to single case studies like Graham.

Some people with Cotard’s have reportedly died of starvation, believing they no longer needed to eat. Others have attempted to get rid of their body using acid, which they saw as the only way they could free themselves of being the “walking dead”.

Graham’s brother and carers made sure he ate, and looked after him. But it was a joyless existence. “I didn’t want to face people. There was no point,” he says, “I didn’t feel pleasure in anything. I used to idolise my car, but I didn’t go near it. All the things I was interested in went away.”

Even the cigarettes he used to relish no longer gave him a hit. “I lost my sense of smell and my sense of taste. There was no point in eating because I was dead. It was a waste of time speaking as I never had anything to say. I didn’t even really have any thoughts. Everything was meaningless.”

Low metabolism

A peek inside Graham’s brain provided Zeman and Laureys with some explanation. They used positron emission tomography to monitor metabolism across his brain. It was the first PET scan ever taken of a person with Cotard’s. What they found was shocking: metabolic activity across large areas of the frontal and parietal brain regions was so low that it resembled that of someone in a vegetative state.

…

Graham says he didn’t really have any thoughts about his future during that time. “I had no other option other than to accept the fact that I had no way to actually die. It was a nightmare.”

Graveyard haunt

This feeling prompted him on occasion to visit the local graveyard. “I just felt I might as well stay there. It was the closest I could get to death. The police would come and get me, though, and take me back home.”

There were some unexplained consequences of the disorder. Graham says he used to have “nice hairy legs”. But after he got Cotard’s, all the hairs fell out. “I looked like a plucked chicken! Saves shaving them I suppose…”

It’s nice to hear him joke. Over time, and with a lot of psychotherapy and drug treatment, Graham has gradually improved and is no longer in the grip of the disorder. He is now able to live independently. “His Cotard’s has ebbed away and his capacity to take pleasure in life has returned,” says Zeman.

“I couldn’t say I’m really back to normal, but I feel a lot better now and go out and do things around the house,” says Graham. “I don’t feel that brain-dead any more. Things just feel a bit bizarre sometimes.” And has the experience changed his feeling about death? “I’m not afraid of death,” he says. “But that’s not to do with what happened – we’re all going to die sometime. I’m just lucky to be alive now.”

Read the entire article here.

Image courtesy of Wikimedia / Public domain.

BigBang, Environs

Your Home As Eco-System

For centuries biologists, zoologists and ecologists have been mapping the wildlife that surrounds us in the great outdoors. Now a group led by microbiologist Noah Fierer at the University of Colorado Boulder is pursuing flora and fauna in one of the last unexplored eco-systems — the home. (Not for the faint of heart).

From the New York Times:

On a sunny Wednesday, with a faint haze hanging over the Rockies, Noah Fierer eyed the field site from the back of his colleague’s Ford Explorer. Two blocks east of a strip mall in Longmont, one of the world’s last underexplored ecosystems had come into view: a sandstone-colored ranch house, code-named Q. A pair of dogs barked in the backyard.

Dr. Fierer, 39, a microbiologist at the University of Colorado Boulder and self-described “natural historian of cooties,” walked across the front lawn and into the house, joining a team of researchers inside. One swabbed surfaces with sterile cotton swabs. Others logged the findings from two humming air samplers: clothing fibers, dog hair, skin flakes, particulate matter and microbial life.

Ecologists like Dr. Fierer have begun peering into an intimate, overlooked world that barely existed 100,000 years ago: the great indoors. They want to know what lives in our homes with us and how we “colonize” spaces with other species — viruses, bacteria, microbes. Homes, they’ve found, contain identifiable ecological signatures of their human inhabitants. Even dogs exert a significant influence on the tiny life-forms living on our pillows and television screens. Once ecologists have more thoroughly identified indoor species, they hope to come up with strategies to scientifically manage homes, by eliminating harmful taxa and fostering species beneficial to our health.

But the first step is simply to take a census of what’s already living with us, said Dr. Fierer; only then can scientists start making sense of their effects. “We need to know what’s out there first. If you don’t know that, you’re wandering blind in the wilderness.”

Here’s an undeniable fact: We are an indoor species. We spend close to 90 percent of our lives in drywalled caves. Yet traditionally, ecologists ventured outdoors to observe nature’s biodiversity, in the Amazon jungles, the hot springs of Yellowstone or the subglacial lakes of Antarctica. (“When you train as an ecologist, you imagine yourself tromping around in the forest,” Dr. Fierer said. “You don’t imagine yourself swabbing a toilet seat.”)

But as humdrum as a home might first appear, it is a veritable wonderland. Ecology does not stop at the front door; a home to you is also home to an incredible array of wildlife.

Besides the charismatic fauna commonly observed in North American homes — dogs, cats, the occasional freshwater fish — ants and roaches, crickets and carpet bugs, mites and millions upon millions of microbes, including hundreds of multicellular species and thousands of unicellular species, also thrive in them. The “built environment” doubles as a complex ecosystem that evolves under the selective pressure of its inhabitants, their behavior and the building materials. As microbial ecologists swab DNA from our homes, they’re creating an atlas of life much as 19th-century naturalists like Alfred Russel Wallace once logged flora and fauna on the Malay Archipelago.

Take an average kitchen. In a study published in February in the journal Environmental Microbiology, Dr. Fierer’s lab examined 82 surfaces in four Boulder kitchens. Predictable patterns emerged. Bacterial species associated with human skin, like Staphylococcaceae or Corynebacteriaceae, predominated. Evidence of soil showed up on the floor, and species associated with raw produce (Enterobacteriaceae, for example) appeared on countertops. Microbes common in moist areas — including sphingomonads, some strains infamous for their ability to survive in the most toxic sites — splashed in a kind of jungle above the faucet.

A hot spot of unrivaled biodiversity was discovered on the stove exhaust vent, probably the result of forced air and settling. The counter and refrigerator, places seemingly as disparate as temperate and alpine grasslands, shared a similar assemblage of microbial species — probably less because of temperature and more a consequence of cleaning. Dr. Fierer’s lab also found a few potential pathogens, like Campylobacter, lurking on the cupboards. There was evidence of the bacterium on a microwave panel, too, presumably a microbial “fingerprint” left by a cook handling raw chicken.

If a kitchen represents a temperate forest, few of its plants would be poison ivy. Most of the inhabitants are relatively benign. In any event, eradicating them is neither possible nor desirable. Dr. Fierer wants to make visible this intrinsic, if unseen, aspect of everyday life. “For a lot of the general public, they don’t care what’s in soil,” he said. “People care more about what’s on their pillowcase.” (Spoiler alert: The microbes living on your pillowcase are not all that different from those living on your toilet seat. Both surfaces come in regular contact with exposed skin.)

Read the entire article after the jump.

Image: Animals commonly found in the home. Courtesy of North Carolina State University.

BigBang

Revisiting Drake

In 1960 radio astronomer Frank Drake began the first systematic search for intelligent signals emanating from space. He was not successful, but his pioneering efforts paved the way for numerous other programs, including SETI (Search for Extra-Terrestrial Intelligence). The Drake Equation is named for him, and put simply, gives an estimate of the number of active, extraterrestrial civilizations with methods of communication in our own galaxy. Drake postulated the equation as a way to get the scientific community engaged in the search for life beyond our home planet.

The Drake equation is:

N = R^{\ast} \cdot f_p \cdot n_e \cdot f_{\ell} \cdot f_i \cdot f_c \cdot L

where:

N = the number of civilizations in our galaxy with which communication might be possible (i.e. which are on our current past light cone); and

R* = the average number of star formation per year in our galaxy

fp = the fraction of those stars that have planets

ne = the average number of planets that can potentially support life per star that has planets

fl = the fraction of planets that could support life that actually develop life at some point

fi = the fraction of planets with life that actually go on to develop intelligent life (civilizations)

fc = the fraction of civilizations that develop a technology that releases detectable signs of their existence into space

L = the length of time for which such civilizations release detectable signals into space

Now, based on recent discoveries of hundreds of extra-solar planets, or exoplanets (those beyond our solar system), by the Kepler space telescope and other Earth-bound observatories, researchers are fine-tuning the original Drake Equation for the 21st century.

From the New Scientist:

An iconic tool in the search for extraterrestrial life is getting a 21st-century reboot – just as our best planet-hunting telescope seems to have died. Though the loss of NASA’s Kepler telescope is a blow, the reboot could mean we find signs of life on extrasolar planets within a decade.

The new tool takes the form of an equation. In 1961 astronomer Frank Drake scribbled his now-famous equation for calculating the number of detectable civilisations in the Milky Way. The Drake equation includes a number of terms that at the time seemed unknowable – including the very existence of planets beyond our solar system.

But the past two decades have seen exoplanets pop up like weeds, particularly in the last few years thanks in large part to the Kepler space telescope. Launched in 2009Movie Camera, Kepler has found more than 130 worlds and detected 3000 or so more possibles. The bounty has given astronomers the first proper census of planets in one region of our galaxy, allowing us to make estimates of the total population of life-friendly worlds across the Milky Way.

With that kind of data in hand, Sara Seager at the Massachusetts Institute of Technology reckons the Drake equation is ripe for a revamp. Her version narrows a few of the original terms to account for our new best bets of finding life, based in part on what Kepler has revealed. If the original Drake equation was a hatchet, the new Seager equation is a scalpel.

Seager presented her work this week at a conference in Cambridge, Massachusetts, entitled “Exoplanets in the Post-Kepler Era”. The timing could not be more prescient. Last week Kepler suffered a surprise hardware failure that knocked out its ability to see planetary signals clearly. If it can’t be fixed, the mission is over.

“When we talked about the post-Kepler era, we thought that would be three to four years from now,” co-organiser David Charbonneau of the Harvard-Smithsonian Center for Astrophysics said last week. “We now know the post-Kepler era probably started two days ago.”

But Kepler has collected data for four years, slightly longer than the mission’s original goal, and so far only the first 18 months’ worth have been analysed. That means it may have already gathered enough information to give alien-hunters a fighting chance.

The original Drake equation includes seven terms, which multiplied together give the number of intelligent alien civilisations we could hope to detect (see diagram). Kepler was supposed to pin down two terms: the fraction of stars that have planets, and the number of those planets that are habitable.

To do that, Kepler had been staring unflinchingly at some 150,000 stars near the constellation Cygnus, looking for periodic changes in brightness caused by a planet crossing, or transiting, a star’s face as seen from Earth. This method tells us a planet’s size and its rough distance from its host star.

Size gives a clue to a planet’s composition, which tells us whether it is rocky like Earth or gassy like Neptune. Before Kepler, only a few exoplanets had been identified as small enough to be rocky, because other search methods were better suited to spotting larger, gas giant worlds.

“Kepler is the single most revolutionary project that has ever been undertaken in exoplanets,” says Charbonneau. “It broke open the piggybank and rocky planets poured out.” A planet’s distance from its star is also crucial, because that tells us whether the temperature is right for liquid water – and so perhaps life – to exist.

But with Kepler’s recent woes, hopes of finding enough potentially habitable planets, or Earth twins, to satisfy the Drake equation have dimmed. The mission was supposed to run for three-and-a-half years, which should have been enough to pinpoint Earth-sized planets with years of a similar length. After the telescope came online, the mission team realised that other sun-like stars are more active than ours, and they bounce around too much in the telescope’s field of view. To find enough Earths, they would need seven or eight years of data.

Read the entire article here.

Image courtesy of the BBC. Drake Equation courtesy of Wikipedia.

BigBang

From RNA Chemistry to Cell Biology

Each day we inch towards a better scientific understanding of how life is thought to have begun on our planet. Over the last decade researchers have shown how molecules like the nucleotides that make up complex chains of RNA (ribonucleic acid) and DNA (deoxyribonucleic acid) may have formed in the primaeval chemical soup of the early Earth. But it’s altogether a much greater leap to get from RNA (or DNA) to even a simple biological cell. Some recent work sheds more light and suggests that the chemical to biological chasm between long-strands of RNA and a complex cell may not be as wide to cross as once thought.

From ars technica:

Origin of life researchers have made impressive progress in recent years, showing that simple chemicals can combine to make nucleotides, the building blocks of DNA and RNA. Given the right conditions, these nucleotides can combine into ever-longer stretches of RNA. A lot of work has demonstrated that RNAs can perform all sorts of interesting chemistry, specifically binding other molecules and catalyzing reactions.

So the case for life getting its start in an RNA world has gotten very strong in the past decade, but the difference between a collection of interesting RNAs and anything like a primitive cell—surrounded by membranes, filled with both RNA and proteins, and running a simple metabolism—remains a very wide chasm. Or so it seems. A set of papers that came out in the past several days suggest that the chasm might not be as large as we’d tend to think.

Ironing out metabolism

A lot of the basic chemistry that drives the cell is based on electron transport, typically involving proteins that contain an iron atom. These reactions not only create some of the basic chemicals that are necessary for life, they’re also essential to powering the cell. Both photosynthesis and the breakdown of sugars involve the transfer of electrons to and from proteins that contain an iron atom.

DNA and RNA tend to have nothing to do with iron, interacting with magnesium instead. But some researchers at Georgia Tech have considered that fact a historical accident. Since photosynthesis put so much oxygen into the atmosphere, most of the iron has been oxidized into a state where it’s not soluble in water. If you go back to before photosynthesis was around, the oceans were filled with dissolved iron. Previously, the group had shown that, in oxygen-free and iron rich conditions, RNAs would happily work with iron instead and that its presence could speed up their catalytic activity.

Now the group is back with a new paper showing that if you put a bunch of random RNAs into the same conditions, some of them can catalyze electron transfer reactions. By “random,” I mean RNAs that are currently used by cells to do completely unrelated things (specifically, ribosomal and transfer RNAs). The reactions they catalyze are very simple, but remember: these RNAs don’t normally function as a catalyst at all. It wouldn’t surprise me if, after a number of rounds of evolutionary selection, an iron-RNA combination could be found that catalyzes a reaction that’s a lot closer to modern metabolism.

All of which suggests that the basics of a metabolism could have gotten started without proteins around.

Proteins build membranes

Clearly, proteins showed up at some point. They certainly didn’t look much like the proteins we see today, which may have hundreds or thousands of amino acids linked together. In fact, they may not have looked much like proteins at all, if a paper from Jack Szostak’s group is any indication. Szostak’s found that just two amino acids linked together may have catalytic activity. Some of that activity can help them engage in competition over another key element of the first cells: membrane material.

The work starts with a two amino acid long chemical called a peptide. If that peptide happens to be serine linked to histidine (two amino acids in use by life today), it has an interesting chemical activity: very slowly and poorly, it links other amino acids together to form more peptides. This weak activity is especially true if the amino acids are phenylalanine and leucine, two water-hating chemicals. Once they’re linked, they will precipitate out of a water solution.

The authors added a fatty acid membrane, figuring that it would soak up the reaction product. That definitely worked, with the catalytic efficiency of serine-histidine going up as a result. But something else happened as well: membranes that incorporated the reaction product started growing. It turns out that its presence in the membrane made it an efficient scrounger of other membrane material. As they grew, these membranes extended as long filaments that would break up into smaller parts with a gentle agitation and then start growing all over again.

In fact, the authors could set up a bit of a Darwinian competition between membranes based on how much starting catalyst each had. All of which suggests that proteins might have found their way into the cell as very simple chemicals that, at least initially, weren’t in any way connected to genetic and biochemical functions performed by RNA. But any cell-like things that evolved an RNA that made short proteins could have a big advantage over its competition.

Read the entire article here.

BigBang

Age is All in the Mind (Hypothalamus)

Researchers are continuing to make great progress in unraveling the complexities of aging. While some fingers point to the shortening of telomeres — end caps — in our chromosomal DNA as a contributing factor, other research points to the hypothalamus. This small sub-region of the brain has been found to play a major role in aging and death (though, at the moment only in mice).

From the New Scientist:

The brain’s mechanism for controlling ageing has been discovered – and manipulated to shorten and extend the lives of mice. Drugs to slow ageing could follow

Tick tock, tick tock… A mechanism that controls ageing, counting down to inevitable death, has been identified in the hypothalamus?– a part of the brain that controls most of the basic functions of life.

By manipulating this mechanism, researchers have both shortened and lengthened the lifespan of mice. The discovery reveals several new drug targets that, if not quite an elixir of youth, may at least delay the onset of age-related disease.

The hypothalamus is an almond-sized puppetmaster in the brain. “It has a global effect,” says Dongsheng Cai at the Albert Einstein College of Medicine in New York. Sitting on top of the brain stem, it is the interface between the brain and the rest of the body, and is involved in, among other things, controlling our automatic response to the world around us, our hormone levels, sleep-wake cycles, immunity and reproduction.

While investigating ageing processes in the brain, Cai and his colleagues noticed that ageing mice produce increasing levels of nuclear factor kB (NF-kB)? ?– a protein complex that plays a major role in regulating immune responses. NF-kB is barely active in the hypothalamus of 3 to 4-month-old mice but becomes very active in old mice, aged 22 to 24 months.

To see whether it was possible to affect ageing by manipulating levels of this protein complex, Cai’s team tested three groups of middle-aged mice. One group was given gene therapy that inhibits NF-kB, the second had gene therapy to activate NF-kB, while the third was left to age naturally.

This last group lived, as expected, between 600 and 1000 days. Mice with activated NF-kB all died within 900 days, while the animals with NF-kB inhibition lived for up to 1100 days.

Crucially, the mice that lived the longest not only increased their lifespan but also remained mentally and physically fit for longer. Six months after receiving gene therapy, all the mice were given a series of tests involving cognitive and physical ability.

In all of the tests, the mice that subsequently lived the longest outperformed the controls, while the short-lived mice performed the worst.

Post-mortem examinations of muscle and bone in the longest-living rodents also showed that they had many chemical and physical qualities of younger mice.

Further investigation revealed that NF-kB reduces the level of a chemical produced by the hypothalamus called gonadotropin-releasing hormone (GnRH) ?– better known for its involvement in the regulation of puberty and fertility, and the production of eggs and sperm.

To see if they could control lifespan using this hormone, the team gave another group of mice??– 20 to 24 months old??– daily subcutaneous injections of GnRH for five to eight weeks. These mice lived longer too, by a length of time similar to that of mice with inhibited NF-kB.

GnRH injections also resulted in new neurons in the brain. What’s more, when injected directly into the hypothalamus, GnRH influenced other brain regions, reversing widespread age-related decline and further supporting the idea that the hypothalamus could be a master controller for many ageing processes.

GnRH injections even delayed ageing in the mice that had been given gene therapy to activate NF-kB and would otherwise have aged more quickly than usual. None of the mice in the study showed serious side effects.

So could regular doses of GnRH keep death at bay? Cai hopes to find out how different doses affect lifespan, but says the hormone is unlikely to prolong life indefinitely since GnRH is only one of many factors at play. “Ageing is the most complicated biological process,” he says.

Read the entire article after the jump.

Image: Location of Hypothalamus. Courtesy of Colorado State University / Wikipedia.

BigBang

General Relativity Lives on For Now

Since Einstein first published his elegant theory of General Relativity almost 100 years ago it has proved to be one of most powerful and enduring cornerstones of modern science. Yet theorists and researchers the world over know that it cannot possibly remain the sole answer to our cosmological questions. It answers questions about the very, very large — galaxies, stars and planets and the gravitational relationship between them. But it fails to tackle the science of the very, very small — atoms, their constituents and the forces that unite and repel them, which is addressed by the elegant and complex, but mutually incompatible Quantum Theory.

So, scientists continue to push their measurements to ever greater levels of precision across both greater and smaller distances with one aim in mind — to test the limits of each theory and to see which one breaks down first.

A recent highly precise and yet very long distance experiment, confirmed that Einstein’s theory still rules the heavens.

From ars technica:

The general theory of relativity is a remarkably successful model for gravity. However, many of the best tests for it don’t push its limits: they measure phenomena where gravity is relatively weak. Some alternative theories predict different behavior in areas subject to very strong gravity, like near the surface of a pulsar—the compact, rapidly rotating remnant of a massive star (also called a neutron star). For that reason, astronomers are very interested in finding a pulsar paired with another high-mass object. One such system has now provided an especially sensitive test of strong gravity.

The system is a binary consisting of a high-mass pulsar and a bright white dwarf locked in mutual orbit with a period of about 2.5 hours. Using optical and radio observations, John Antoniadis and colleagues measured its properties as it spirals toward merger by emitting gravitational radiation. After monitoring the system for a number of orbits, the researchers determined its behavior is in complete agreement with general relativity to a high level of precision.

The binary system was first detected in a survey of pulsars by the Green Bank Telescope (GBT). The pulsar in the system, memorably labeled PSR J0348+0432, emits radio pulses about once every 39 milliseconds (0.039 seconds). Fluctuations in the pulsar’s output indicated that it is in a binary system, though its companion lacked radio emissions. However, the GBT’s measurements were precise enough to pinpoint its location in the sky, which enabled the researchers to find the system in the archives of the Sloan Digital Sky Survey (SDSS). They determined the companion object was a particularly bright white dwarf, the remnant of the core of a star similar to our Sun. It and the pulsar are locked in a mutual orbit about 2.46 hours in length.

Following up with the Very Large Telescope (VLT) in Chile, the astronomers built up enough data to model the system. Pulsars are extremely dense, packing a star’s worth of mass into a sphere roughly 10 kilometers in radius—far too small to see directly. White dwarfs are less extreme, but they still involve stellar masses in a volume roughly equivalent to Earth’s. That means the objects in the PSR J0348+0432 system can orbit much closer to each other than stars could—as little as 0.5 percent of the average Earth-Sun separation, or 1.2 times the Sun’s radius.

The pulsar itself was interesting because of its relatively high mass: about 2.0 times that of the Sun (most observed pulsars are about 1.4 times more massive). Unlike more mundane objects, pulsar size doesn’t grow with mass; according to some models, a higher mass pulsar may actually be smaller than one with lower mass. As a result, the gravity at the surface of PSR J0348+0432 is far more intense than at a lower-mass counterpart, providing a laboratory for testing general relativity (GR). The gravitational intensity near PSR J0348+0432 is about twice that of other pulsars in binary systems, creating a more extreme environment than previously measured.

According to GR, a binary emits gravitational waves that carry energy away from the system, causing the size of the orbit to shrink. For most binaries, the effect is small, but for compact systems like the one containing PSR J0348+0432, it is measurable. The first such system was found by Russel Hulse and Joseph Taylor; its discovery won the two astronomers the Nobel Prize.

The shrinking of the orbit results in a decrease in the orbital period as the two objects revolve around each other more quickly. In this case, the researchers measured the effect by studying the change in the spectrum of light emitted by the white dwarf, as well as fluctuations in the emissions from the pulsar. (This study also helped demonstrate the two objects were in mutual orbit, rather than being coincidentally in the same part of the sky.)

To test agreement with GR, physicists established a set of observable quantities. These include the rate of orbit decrease (which is a reflection of the energy loss to gravitational radiation) and something called the Shapiro delay. The latter phenomenon occurs because light emitted from the pulsar must travel through the intense gravitational field of the pulsar when exiting the system. This effect depends on the relative orientation of the pulsar to us, but alternative models also predict different observable results.

In the case of the PSR J0348+0432 system, the change in orbital period and the Shapiro delay agreed with the predictions of GR, placing strong constraints on alternative theories. The researchers were also able to rule out energy loss from other, non-gravitational sources (rotation or electromagnetic phenomena). If the system continues as models predict, the white dwarf and pulsar will merge in about 400 million years—we don’t know what the product of that merger will be, so astronomers are undoubtedly marking their calendars now.

The results are of potential use for the Laser Interferometer Gravitational-wave Observatory (LIGO) and other ground-based gravitational-wave detectors. These instruments are sensitive to the final death spiral of binaries like the one containing PSR J0348+0432. The current detection and observation strategies involve “templates,” or theoretical models of the gravitational wave signal from binaries. All information about the behavior of close pulsar binaries helps gravitational-wave astronomers refine those templates, which should improve the chances of detection.

Of course, no theory can be “proven right” by experiment or observation—data provides evidence in support of or against the predictions of a particular model. However, the PSR J0348+0432 binary results placed stringent constraints on any alternative model to GR in the strong-gravity regime. (Certain other alternative models focus on altering gravity on large scales to explain dark energy and the acceleration expansion of the Universe.) Based on this new data, only theories that agree with GR to high precision are still standing—leaving general relativity the continuing champion theory of gravity.

Read the entire article after the jump.

Image: Artist’s impression of the PSR J0348+0432 system. The compact pulsar (with beams of radio emission) produces a strong distortion of spacetime (illustrated by the green mesh). Courtesy of Science Mag.

BigBang, tD

Your Genes. But Are They Your Intellectual Property?

The genetic code buried deep within your cells, described in a unique sequence encoded in your DNA, defines who you are at the most fundamental level. The 20,000 or so genes in your genome establish how you are constructed and how you function (and malfunction). These genes are common to many, but their expression belongs to only you.

Yet, companies are out to patent strings of this genetic code. While many would argue that patent ownership is a sound business strategy, in most industries, it is morally indefensible in this case. Rafts of bio-ethicists have argued the pros and cons of patenting animal and human genetic information for decades, and as we speak a case has made it to the U.S. Supreme Court. Can a company claim ownership of your genetic code? While the rights of business over those of an individual’s genetic code are dubious at best, it is clear that public consensus and a clear ethical framework, and consequently a sound legal doctrine, lag far behind the actual science.

From the Guardian

Tracey Barraclough made a grim discovery in 1998. She found she possessed a gene that predisposed her to cancer. “I was told I had up to an 85% chance of developing breast cancer and an up to 60% chance of developing ovarian cancer,” she recalls. The piece of DNA responsible for her grim predisposition is known as the BRCA1 gene.

Tracey was devastated, but not surprised. She had sought the gene test because her mother, grandmother and great-grandmother had all died of ovarian cancer in their 50s. Four months later Tracey had her womb and ovaries removed to reduce her cancer risk. A year later she had a double mastectomy.

“Deciding to embark on that was the loneliest and most agonising journey of my life,” Tracey says. “My son, Josh, was five at the time and I wanted to live for him. I didn’t want him to grow up without a mum.” Thirteen years later, Tracey describes herself as “100% happy” with her actions. “It was the right thing for me. I feel that losing my mother, grandmother and great-grandmother hasn’t been in vain.”

The BRCA1 gene that Tracey inherited is expressed in breast tissue where it helps repair damaged DNA. In its mutated form, found in a small percentage of women, damaged DNA cannot be repaired and carriers become highly susceptible to cancers of the breast and ovaries.

The discovery of BRCA1 in 1994, and a second version, BRCA2, discovered a year later, remains one of the greatest triumphs of modern genetics. It allows doctors to pinpoint women at high risk of breast or ovarian cancer in later life. Stars such as Sharon Osbourne and Christina Applegate have been among those who have had BRCA1 diagnoses and subsequent mastectomies. BRCA technology has saved many lives over the years. However, it has also triggered a major division in the medical community, a split that last week ended up before the nine justices of the US supreme court. At issue is the simple but fundamental question: should the law allow companies to patent human genes? It is a battle that has profound implications for genetic research and has embroiled scientists on both sides of the Atlantic in a major argument about the nature of scientific inquiry.

On one side, US biotechnology giant Myriad Genetics is demanding that the US supreme court back the patents it has taken out on the BRCA genes. The company believes it should be the only producer of tests to detect mutations in these genes, a business it has carried out in the United States for more than a decade.

On the other side, a group of activists, represented by lawyers from the American Civil Liberties Union, argues that it is fundamentally absurd and immoral to claim ownership of humanity’s shared genetic heritage and demands that the court ban patents. How can anyone think that any individual or company should enjoy exclusive use of naturally occurring DNA sequences pertinent to human diseases, they ask?

It is a point stressed by Gilda Witte, head of Ovarian Cancer Action in the UK. “The idea that you can hold a patent to a piece of human DNA is just wrong. More and more genes that predispose individuals to cancers and other conditions are being discovered by scientists all the time. If companies like Myriad are allowed to hold more and more patents like the ones they claim for BRCA1 and BRCA2, the cost of diagnosing disease is going to soar.”

For its part, Myriad denies it has tried to patent human DNA on its own. Instead, the company argues that its patents cover the techniques it has developed to isolate the BRCA1 and BRCA2 genes and the chemical methods it has developed to make it possible to analyse the genes in the laboratory. Mark Capone, the president of Myriad, says his company has invested $500m in developing its BRCA tests.

“It is certainly true that people will not invest in medicine unless there is some return on that investment,” said Justin Hitchcock, a UK expert on patent law and medicine. “That is why Myriad has sought these patents.”

In Britain, women such as Tracey Barraclough have been given BRCA tests for free on the NHS. In the US, where Myriad holds patents, those seeking such tests have to pay the company $4,000. It might therefore seem to be a peculiarly American debate based on the nation’s insistence on having a completely privatised health service. Professor Alan Ashworth, director of the Institute for Cancer Research, disagreed, however.

“I think that, if Myriad win this case, the impact will be retrograde for the whole of genetic research across the globe,” he said. “The idea that you can take a piece of DNA and claim that only you are allowed to test for its existence is wrong. It stinks, morally and intellectually. People are becoming easier about using and exchanging genetic information at present. Any move to back Myriad would take us back decades.”

Issuing patents is a complicated business, of course, a point demonstrated by the story of monoclonal antibodies. Developed in British university labs in the 1970s, these artificial versions of natural antibodies won a Nobel prize in 1984 for their inventors, a team led by César Milstein at Cambridge University. Monoclonal antibodies target disease sites in the human body and can be fitted with toxins to be sent like tiny Exocet missiles to carry their lethal payloads straight to a tumour.

When Milstein and his team finished their research, they decided to publish their results straight away. Once in the public domain, the work could no longer claim patent protection, a development that enraged the newly elected prime minister, Margaret Thatcher, a former patent lawyer. She, and many others, viewed the monoclonal story as a disaster that could have cost Britain billions.

But over the years this view has become less certain. “If you look at medicines based on monoclonal antibodies today, it is clear these are some of the most valuable on the market,” said Hitchcock. “But that value is based on the layers of inventiveness that have since been added to the basic concept of the monoclonal antibody and has nothing to do with the actual technique itself.”

Read the entire article following the jump.

Image: A museum visitor views a digital representation of the human genome in New York City in 2001. Courtesy of Mario Tama, Getty Images / National Geographic.

BigBang

One Way Ticket to Mars

You would be rightfully mistaken for thinking this might be a lonesome bus trip to Mars, Pennsylvania or to the North American headquarters of Mars, purveyors of many things chocolaty including M&Ms, Mars Bars and Snickers, in New Jersey. This one way ticket is further afield, to the Red Planet, and comes from a company known as Mars One — estimated time of departure, 2023.

From the Guardian:

A few months before he died, Carl Sagan recorded a message of hope to would-be Mars explorers, telling them: “Whatever the reason you’re on Mars is, I’m glad you’re there. And I wish I was with you.”

On Monday, 17 years after the pioneering astronomer set out his hopeful vision of the future in 1996, a company from the Netherlands is proposing to turn Sagan’s dreams of reaching Mars into reality. The company, Mars One, plans to send four astronauts on a trip to the Red Planet to set up a human colony in 2023. But there are a couple of serious snags.

Firstly, when on Mars their bodies will have to adapt to surface gravity that is 38% of that on Earth. It is thought that this would cause such a total physiological change in their bone density, muscle strength and circulation that voyagers would no longer be able to survive in Earth’s conditions. Secondly, and directly related to the first, they will have to say goodbye to all their family and friends, as the deal doesn’t include a return ticket.

The Mars One website states that a return “cannot be anticipated nor expected”. To return, they would need a fully assembled and fuelled rocket capable of escaping the gravitational field of Mars, on-board life support systems capable of up to a seven-month voyage and the capacity either to dock with a space station orbiting Earth or perform a safe re-entry and landing.

“Not one of these is a small endeavour” the site notes, requiring “substantial technical capacity, weight and cost”.

Nevertheless, the project has already had 10,000 applicants, according to the company’s medical director, Norbert Kraft. When the official search is launched on Monday at the Hotel Pennsylvania in New York, they expect tens of thousands more hopefuls to put their names forward.

Kraft told the Guardian that the applicants so far ranged in age from 18 to at least 62 and, though they include women, they tended to be men.

The reasons they gave for wanting to go were varied, he said. One of three examples Kraft forwarded by email to the Guardian cited Sagan.

An American woman called Cynthia, who gave her age as 32, told the company that it was a “childhood imagining” of hers to go to Mars. She described a trip her mother had taken her on in the early 1990s to a lecture at the University of Wisconsin.

In a communication to Mars One, she said the lecturer had been Sagan and she had asked him if he thought humans would land on Mars in her lifetime. Cynthia said: “He in turn asked me if I wanted to be trapped in a ‘tin can spacecraft’ for the two years it would take to get there. I told him yes, he smiled, and told me in all seriousness, that yes, he absolutely believed that humans would reach Mars in my lifetime.”

She told the project: “When I first heard about the Mars One project I thought, this is my chance – that childhood dream could become a reality. I could be one of the pioneers, building the first settlement on Mars and teaching people back home that there are still uncharted territories that humans can reach for.”

The prime attributes Mars One is looking for in astronaut-settlers is resilience, adaptability, curiosity, ability to trust and resourcefulness, according to Kraft. They must also be over 18.

Professor Gerard ‘t Hooft, winner of the Nobel prize for theoretical physics in 1999 and lecturer of theoretical physics at the University of Utrecht, Holland, is an ambassador for the project. ‘T Hooft admits there are unknown health risks. The radiation is “of quite a different nature” than anything that has been tested on Earth, he told the BBC.

Founded in 2010 by Bas Lansdorp, an engineer, Mars One says it has developed a realistic road map and financing plan for the project based on existing technologies and that the mission is perfectly feasible. The website states that the basic elements required for life are already present on the planet. For instance, water can be extracted from ice in the soil and Mars has sources of nitrogen, the primary element in the air we breathe. The colony will be powered by specially adapted solar panels, it says.

In March, Mars One said it had signed a contract with the American firm Paragon Space Development Corporation to take the first steps in developing the life support system and spacesuits fit for the mission.

The project will cost a reported $6bn (£4bn), a sum Lansdorp has said he hopes will be met partly by selling broadcasting rights. “The revenue garnered by the London Olympics was almost enough to finance a mission to Mars,” Lansdorp said, in an interview with ABC News in March.

Another ambassador to the project is Paul Römer, the co-creator of Big Brother, one of the first reality TV shows and one of the most successful.

On the website, Römer gave an indication of how the broadcasting of the project might proceed: “This mission to Mars can be the biggest media event in the world,” said Römer. “Reality meets talent show with no ending and the whole world watching. Now there’s a good pitch!”

The aim is to establish a permanent human colony, according to the company’s website. The first team would land on the surface of Mars in 2023 to begin constructing the colony, with a team of four astronauts every two years after that.

The project is not without its sceptics, however, and concerns have been raised about how astronauts might get to the surface and establish a colony with all the life support and other requirements needed. There were also concerns over the health implications for the applicants.

Dr Veronica Bray, from the University of Arizona’s lunar and planetary laboratory, told BBC News that Earth was protected from solar winds by a strong magnetic field, without which it would be difficult to survive. The Martian surface is very hostile to life. There is no liquid water, the atmospheric pressure is “practically a vacuum”, radiation levels are higher and temperatures vary wildly. High radiation levels can lead to increased cancer risk, a lowered immune system and possibly infertility, she said.

To minimise radiation, the project team will cover the domes they plan to build with several metres of soil, which the colonists will have to dig up.

The mission hopes to inspire generations to “believe that all things are possible, that anything can be achieved” much like the Apollo moon landings.

“Mars One believes it is not only possible, but imperative that we establish a permanent settlement on Mars in order to accelerate our understanding of the formation of the solar system, the origins of life, and of equal importance, our place in the universe” it says.

Read the entire article following the jump.

Image: Panoramic View From ‘Rocknest’ Position of Curiosity Mars Rover. Courtesy of JPL / NASA.

BigBang

Idyllic Undeveloped Land: Only 1,200 Light Years Away

Humans may soon make their only home irreversibly uninhabitable. Fortunately, astronomers have recently discovered a couple of exo-planets capable of sustaining life. Unfortunately, they are a little too distant — using current technology it would take humans around 26 million years. But, we can still dream.

From the New York Times:

Astronomers said Thursday that they had found the most Earth-like worlds yet known in the outer cosmos, a pair of planets that appear capable of supporting life and that orbit a star 1,200 light-years from here, in the northern constellation Lyra.

They are the two outermost of five worlds circling a yellowish star slightly smaller and dimmer than our Sun, heretofore anonymous and now destined to be known in the cosmic history books as Kepler 62, after NASA’s Kepler spacecraft, which discovered them. These planets are roughly half again as large as Earth and are presumably balls of rock, perhaps covered by oceans with humid, cloudy skies, although that is at best a highly educated guess.

Nobody will probably ever know if anything lives on these planets, and the odds are that humans will travel there only in their faster-than-light dreams, but the news has sent astronomers into heavenly raptures. William Borucki of NASA’s Ames Research Center, head of the Kepler project, described one of the new worlds as the best site for Life Out There yet found in Kepler’s four-years-and-counting search for other Earths. He treated his team to pizza and beer on his own dime to celebrate the find (this being the age of sequestration). “It’s a big deal,” he said.

Looming brightly in each other’s skies, the two planets circle their star at distances of 37 million and 65 million miles, about as far apart as Mercury and Venus in our solar system. Most significantly, their orbits place them both in the “Goldilocks” zone of lukewarm temperatures suitable for liquid water, the crucial ingredient for Life as We Know It.

Goldilocks would be so jealous.

Previous claims of Goldilocks planets with “just so” orbits snuggled up to red dwarf stars much dimmer and cooler than the Sun have had uncertainties in the size and mass and even the existence of these worlds, said David Charbonneau of the Harvard-Smithsonian Center for Astrophysics, an exoplanet hunter and member of the Kepler team.

“This is the first planet that ticks both boxes,” Dr. Charbonneau said, speaking of the outermost planet, Kepler 62f. “It’s the right size and the right temperature.” Kepler 62f is 40 percent bigger than Earth and smack in the middle of the habitable zone, with a 267-day year. In an interview, Mr. Borucki called it the best planet Kepler has found.

Its mate, known as Kepler 62e, is slightly larger — 60 percent bigger than Earth — and has a 122-day orbit, placing it on the inner edge of the Goldilocks zone. It is warmer but also probably habitable, astronomers said.

The Kepler 62 system resembles our own solar system, which also has two planets in the habitable zone: Earth — and Mars, which once had water and would still be habitable today if it were more massive and had been able to hang onto its primordial atmosphere.

The Kepler 62 planets continue a string of breakthroughs in the last two decades in which astronomers have gone from detecting the first known planets belonging to other stars, or exoplanets, broiling globs of gas bigger than Jupiter, to being able to discern smaller and smaller more moderate orbs — iceballs like Neptune and, now, bodies only a few times the mass of Earth, known technically as super-Earths. Size matters in planetary affairs because we can’t live under the crushing pressure of gas clouds on a world like Jupiter. Life as We Know It requires solid ground and liquid water — a gentle terrestrial environment, in other words.

Kepler 62’s newfound worlds are not quite small enough to be considered strict replicas of Earth, but the results have strengthened the already strong conviction among astronomers that the galaxy is littered with billions of Earth-size planets, perhaps as many as one per star, and that astronomers will soon find Earth 2.0, as they call it — our lost twin bathing in the rays of an alien sun.

“Kepler and other experiments are finding planets that remind us more and more of home,” said Geoffrey Marcy, a longtime exoplanet hunter at the University of California, Berkeley, and Kepler team member. “It’s an amazing moment in science. We haven’t found Earth 2.0 yet, but we can taste it, smell it, right there on our technological fingertips.”

Read the entire article following the jump.

Image: The Kepler 62 system: homes away from home. Courtesy of JPL-Caltech/Ames/NASA.

BigBang, Technica

Off World Living

Will humanity ever transcend gravity to become a space-faring race? A simple napkin-based calculation will give you the answer.

From Scientific American:

Optimistic visions of a human future in space seem to have given way to a confusing mix of possibilities, maybes, ifs, and buts. It’s not just the fault of governments and space agencies, basic physics is in part the culprit. Hoisting mass away from Earth is tremendously difficult, and thus far in fifty years we’ve barely managed a total the equivalent of a large oil-tanker. But there’s hope.

Back in the 1970?s the physicist Gerard O’Neill and his students investigated concepts of vast orbital structures capable of sustaining entire human populations. It was the tail end of the Apollo era, and despite the looming specter of budget restrictions and terrestrial pessimism there was still a sense of what might be, what could be, and what was truly within reach.

The result was a series of blueprints for habitats that solved all manner of problems for space life, from artificial gravity (spin up giant cylinders), to atmospheres, and radiation (let the atmosphere shield you). They’re pretty amazing, and they’ve remained perhaps one of the most optimistic visions of a future where we expand beyond the Earth.

But there’s a lurking problem, and it comes down to basic physics. It is awfully hard to move stuff from the surface of our planet into orbit or beyond. O’Neill knew this, as does anyone else who’s thought of grand space schemes. The solution is to ‘live of the land’, extracting raw materials from either the Moon with its shallower gravity well, or by processing asteroids. To get to that point though we’d still have to loft an awful lot of stuff into space – the basic tools and infrastructure have to start somewhere.

And there’s the rub. To put it into perspective I took a look at the amount of ‘stuff’ we’ve managed to get off Earth in the past 50-60 years. It’s actually pretty hard to evaluate, lots of the mass we send up comes back down in short order – either as spent rocket stages or as short-lived low-altitude satellites. But we can still get a feel for it.

To start with, a lower limit on the mass hoisted to space is the present day artificial satellite population. Altogether there are in excess of about 3,000 satellites up there, plus vast amounts of small debris. Current estimates suggest this amounts to a total of around 6,000 metric tons. The biggest single structure is the International Space Station, currently coming in at about 450 metric tons (about 992,000 lb for reference).

These numbers don’t reflect launch mass – the total of a rocket + payload + fuel. To put that into context, a fully loaded Saturn V was about 2,000 metric tons, but most of that was fuel.

When the Space Shuttle flew it amounted to about 115 metric tons (Shuttle + payload) making it into low-Earth orbit. Since there were 135 launches of the Shuttle that amounts to a total hoisted mass of about 15,000 metric tons over a 30 year period.

Read the entire article after the jump.

Image: A pair of O’Neill cylinders. NASA ID number AC75-1085. Courtesy of NASA / Wikipedia.

BigBang, Technica

Ray Kurzweil and Living a Googol Years

By all accounts serial entrepreneur, inventor and futurist Ray Kurzweil is Google’s most famous employee, eclipsing even co-founders Larry Page and Sergei Brin. As an inventor he can lay claim to some impressive firsts, such as the flatbed scanner, optical character recognition and the music synthesizer. As a futurist, for which he is now more recognized in the public consciousness, he ponders longevity, immortality and the human brain.

From the Wall Street Journal:

Ray Kurzweil must encounter his share of interviewers whose first question is: What do you hope your obituary will say?

This is a trick question. Mr. Kurzweil famously hopes an obituary won’t be necessary. And in the event of his unexpected demise, he is widely reported to have signed a deal to have himself frozen so his intelligence can be revived when technology is equipped for the job.

Mr. Kurzweil is the closest thing to a Thomas Edison of our time, an inventor known for inventing. He first came to public attention in 1965, at age 17, appearing on Steve Allen’s TV show “I’ve Got a Secret” to demonstrate a homemade computer he built to compose original music in the style of the great masters.

In the five decades since, he has invented technologies that permeate our world. To give one example, the Web would hardly be the store of human intelligence it has become without the flatbed scanner and optical character recognition, allowing printed materials from the pre-digital age to be scanned and made searchable.

If you are a musician, Mr. Kurzweil’s fame is synonymous with his line of music synthesizers (now owned by Hyundai). As in: “We’re late for the gig. Don’t forget the Kurzweil.”

If you are blind, his Kurzweil Reader relieved one of your major disabilities—the inability to read printed information, especially sensitive private information, without having to rely on somebody else.

In January, he became an employee at Google. “It’s my first job,” he deadpans, adding after a pause, “for a company I didn’t start myself.”

There is another Kurzweil, though—the one who makes seemingly unbelievable, implausible predictions about a human transformation just around the corner. This is the Kurzweil who tells me, as we’re sitting in the unostentatious offices of Kurzweil Technologies in Wellesley Hills, Mass., that he thinks his chances are pretty good of living long enough to enjoy immortality. This is the Kurzweil who, with a bit of DNA and personal papers and photos, has made clear he intends to bring back in some fashion his dead father.

Mr. Kurzweil’s frank efforts to outwit death have earned him an exaggerated reputation for solemnity, even caused some to portray him as a humorless obsessive. This is wrong. Like the best comedians, especially the best Jewish comedians, he doesn’t tell you when to laugh. Of the pushback he receives from certain theologians who insist death is necessary and ennobling, he snarks, “Oh, death, that tragic thing? That’s really a good thing.”

“People say, ‘Oh, only the rich are going to have these technologies you speak of.’ And I say, ‘Yeah, like cellphones.’ “

To listen to Mr. Kurzweil or read his several books (the latest: “How to Create a Mind”) is to be flummoxed by a series of forecasts that hardly seem realizable in the next 40 years. But this is merely a flaw in my brain, he assures me. Humans are wired to expect “linear” change from their world. They have a hard time grasping the “accelerating, exponential” change that is the nature of information technology.

“A kid in Africa with a smartphone is walking around with a trillion dollars of computation circa 1970,” he says. Project that rate forward, and everything will change dramatically in the next few decades.

“I’m right on the cusp,” he adds. “I think some of us will make it through”—he means baby boomers, who can hope to experience practical immortality if they hang on for another 15 years.

By then, Mr. Kurzweil expects medical technology to be adding a year of life expectancy every year. We will start to outrun our own deaths. And then the wonders really begin. The little computers in our hands that now give us access to all the world’s information via the Web will become little computers in our brains giving us access to all the world’s information. Our world will become a world of near-infinite, virtual possibilities.

How will this work? Right now, says Mr. Kurzweil, our human brains consist of 300 million “pattern recognition” modules. “That’s a large number from one perspective, large enough for humans to invent language and art and science and technology. But it’s also very limiting. Maybe I’d like a billion for three seconds, or 10 billion, just the way I might need a million computers in the cloud for two seconds and can access them through Google.”

We will have vast new brainpower at our disposal; we’ll also have a vast new field in which to operate—virtual reality. “As you go out to the 2040s, now the bulk of our thinking is out in the cloud. The biological portion of our brain didn’t go away but the nonbiological portion will be much more powerful. And it will be uploaded automatically the way we back up everything now that’s digital.”

“When the hardware crashes,” he says of humanity’s current condition, “the software dies with it. We take that for granted as human beings.” But when most of our intelligence, experience and identity live in cyberspace, in some sense (vital words when thinking about Kurzweil predictions) we will become software and the hardware will be replaceable.

Read the entire article after the jump.

BigBang, Environs

Dark Lightning

It’s fascinating how a seemingly well-understood phenomenon, such as lightning, can still yield enormous surprises. Researchers have found that visible flashes of lightning can also be accompanied by non-visible, and more harmful, radiation such as x- and gamma-rays.

From the Washington Post:

A lightning bolt is one of nature’s most over-the-top phenomena, rarely failing to elicit at least a ping of awe no matter how many times a person has witnessed one. With his iconic kite-and-key experiments in the mid-18th century, Benjamin Franklin showed that lightning is an electrical phenomenon, and since then the general view has been that lightning bolts are big honking sparks no different in kind from the little ones generated by walking in socks across a carpeted room.

But scientists recently discovered something mind-bending about lightning: Sometimes its flashes are invisible, just sudden pulses of unexpectedly powerful radiation. It’s what Joseph Dwyer, a lightning researcher at the Florida Institute of Technology, has termed dark lightning.

Unknown to Franklin but now clear to a growing roster of lightning researchers and astronomers is that along with bright thunderbolts, thunderstorms unleash sprays of X-rays and even intense bursts of gamma rays, a form of radiation normally associated with such cosmic spectacles as collapsing stars. The radiation in these invisible blasts can carry a million times as much energy as the radiation in visible lightning, but that energy dissipates quickly in all directions rather than remaining in a stiletto-like lightning bolt.

Dark lightning appears sometimes to compete with normal lightning as a way for thunderstorms to vent the electrical energy that gets pent up inside their roiling interiors, Dwyer says. Unlike with regular lightning, though, people struck by dark lightning, most likely while flying in an airplane, would not get hurt. But according to Dwyer’s calculations, they might receive in an instant the maximum safe lifetime dose of ionizing radiation — the kind that wreaks the most havoc on the human body.

The only way to determine whether an airplane had been struck by dark lightning, Dwyer says, “would be to use a radiation detector. Right in the middle of [a flash], a very brief bluish-purple glow around the plane might be perceptible. Inside an aircraft, a passenger would probably not be able to feel or hear much of anything, but the radiation dose could be significant.”

However, because there’s only about one dark lightning occurrence for every thousand visible flashes and because pilots take great pains to avoid thunderstorms, Dwyer says, the risk of injury is quite limited. No one knows for sure if anyone has ever been hit by dark lightning.

About 25 million visible thunderbolts hit the United States every year, killing about 30 people and many farm animals, says John Jensenius, a lightning safety specialist with the National Weather Service in Gray, Maine. Worldwide, thunderstorms produce about a billion or so lightning bolts annually.

Read the entire article after the jump.

Image: Lightning in Foshan, China. Courtesy of Telegraph.

BigBang

The Dangerous World of Pseudo-Academia

Pseudoscience can be fun — for comedic purposes only of course. But when it is taken seriously and dogmatically, as it often is by a significant number of people, it imperils rational dialogue and threatens real scientific and cultural progress. There is no end to the lengthy list of fake scientific claims and theories — some of our favorites include: the moon “landing” conspiracy, hollow Earth, Bermuda triangle, crop circles, psychic surgery, body earthing, room temperature fusion, perpetual and motion machines.

Fun aside, pseudoscience can also be harmful and dangerous particularly when those duped by the dubious practice are harmed physically, medically or financially. Which brings us to a recent, related development aimed at duping academics. Welcome to the world of pseudo-academia.

From the New York Times:

The scientists who were recruited to appear at a conference called Entomology-2013 thought they had been selected to make a presentation to the leading professional association of scientists who study insects.

But they found out the hard way that they were wrong. The prestigious, academically sanctioned conference they had in mind has a slightly different name: Entomology 2013 (without the hyphen). The one they had signed up for featured speakers who were recruited by e-mail, not vetted by leading academics. Those who agreed to appear were later charged a hefty fee for the privilege, and pretty much anyone who paid got a spot on the podium that could be used to pad a résumé.

“I think we were duped,” one of the scientists wrote in an e-mail to the Entomological Society.

Those scientists had stumbled into a parallel world of pseudo-academia, complete with prestigiously titled conferences and journals that sponsor them. Many of the journals and meetings have names that are nearly identical to those of established, well-known publications and events.

Steven Goodman, a dean and professor of medicine at Stanford and the editor of the journal Clinical Trials, which has its own imitators, called this phenomenon “the dark side of open access,” the movement to make scholarly publications freely available.

The number of these journals and conferences has exploded in recent years as scientific publishing has shifted from a traditional business model for professional societies and organizations built almost entirely on subscription revenues to open access, which relies on authors or their backers to pay for the publication of papers online, where anyone can read them.

Open access got its start about a decade ago and quickly won widespread acclaim with the advent of well-regarded, peer-reviewed journals like those published by the Public Library of Science, known as PLoS. Such articles were listed in databases like PubMed, which is maintained by the National Library of Medicine, and selected for their quality.

But some researchers are now raising the alarm about what they see as the proliferation of online journals that will print seemingly anything for a fee. They warn that nonexperts doing online research will have trouble distinguishing credible research from junk. “Most people don’t know the journal universe,” Dr. Goodman said. “They will not know from a journal’s title if it is for real or not.”

Researchers also say that universities are facing new challenges in assessing the résumés of academics. Are the publications they list in highly competitive journals or ones masquerading as such? And some academics themselves say they have found it difficult to disentangle themselves from these journals once they mistakenly agree to serve on their editorial boards.

The phenomenon has caught the attention of Nature, one of the most competitive and well-regarded scientific journals. In a news report published recently, the journal noted “the rise of questionable operators” and explored whether it was better to blacklist them or to create a “white list” of those open-access journals that meet certain standards. Nature included a checklist on “how to perform due diligence before submitting to a journal or a publisher.”

Jeffrey Beall, a research librarian at the University of Colorado in Denver, has developed his own blacklist of what he calls “predatory open-access journals.” There were 20 publishers on his list in 2010, and now there are more than 300. He estimates that there are as many as 4,000 predatory journals today, at least 25 percent of the total number of open-access journals.

“It’s almost like the word is out,” he said. “This is easy money, very little work, a low barrier start-up.”

Journals on what has become known as “Beall’s list” generally do not post the fees they charge on their Web sites and may not even inform authors of them until after an article is submitted. They barrage academics with e-mail invitations to submit articles and to be on editorial boards.

One publisher on Beall’s list, Avens Publishing Group, even sweetened the pot for those who agreed to be on the editorial board of The Journal of Clinical Trails & Patenting, offering 20 percent of its revenues to each editor.

One of the most prolific publishers on Beall’s list, Srinubabu Gedela, the director of the Omics Group, has about 250 journals and charges authors as much as $2,700 per paper. Dr. Gedela, who lists a Ph.D. from Andhra University in India, says on his Web site that he “learnt to devise wonders in biotechnology.”

Read the entire article following the jump.

Image courtesy of University of Texas.

BigBang

Looking for Alien Engineering Work

We haven’t yet found any aliens inhabiting exoplanets orbiting distant stars. We haven’t received any intelligently manufactured radio signals from deep space. And, unless you subscribe to the conspiracy theories surrounding Roswell Area 51, it’s unlikely that we’ve been visited by an extra-terrestrial intelligence.

Most reasonable calculations suggest that the universe should be teeming with life beyond our small, blue planet. So, where are all the aliens and why haven’t we been contacted yet? Not content to wait, some astronomers believe we should be looking for evidence of distant alien engineering projects.

From the New Scientist:

ALIENS: where are you? Our hopes of finding intelligent companionship seem to be constantly receding. Mars and Venus are not the richly populated realms we once guessed at. The icy seas of the outer solar system may hold life, but almost certainly no more than microbes. And the search for radio signals from more distant extraterrestrials has so frustrated some astronomers that they are suggesting we shout out an interstellar “Hello”, in the hope of prodding the dozy creatures into a response.

So maybe we need to think along different lines. Rather than trying to intercept alien communications, perhaps we should go looking for alien artefacts.

There have already been a handful of small-scale searches, but now three teams of astronomers are setting out to scan a much greater volume of space (see diagram). Two groups hope to see the shadows of alien industry in fluctuating starlight. The third, like archaeologists sifting through a midden heap on Earth, is hunting for alien waste.

What they’re after is something rather grander than flint arrowheads or shards of pottery. Something big. Planet-sized power stations. Star-girdling rings or spheres. Computers the size of a solar system. Perhaps even an assembly of hardware so vast it can darken an entire galaxy.

It might seem crazy to even entertain the notion of such stupendous celestial edifices, let alone go and look for them. Yet there is a simple rationale. Unless tool-users are always doomed to destroy themselves, any civilisation out there is likely to be far older and far more advanced than ours.

Humanity has already covered vast areas of Earth’s surface with roads and cities, and begun sending probes to other planets. If we can do all this in a matter of centuries, what could more advanced civilisations do over many thousands or even millions of years?

In 1960, the physicist Freeman Dyson pointed out that if alien civilisations keep growing and expanding, they will inevitably consume ever more energy – and the biggest source of energy in any star system is the star itself. Our total power consumption today is equivalent to about 0.01 per cent of the sunlight falling on Earth, so solar power could easily supply all our needs. If energy demand keeps growing at 1 per cent a year, however, then in 1000 years we’d need more energy than strikes the surface of the planet. Other energy sources, such as nuclear fusion, cannot solve the problem because the waste heat would fry the planet.

In a similar position, alien civilisations could start building solar power plants, factories and even habitats in space. With material mined from asteroids, then planets, and perhaps even the star itself, they could really spread out. Dyson’s conclusion was that after thousands or millions of years, the star might be entirely surrounded by a vast artificial sphere of solar panels.

The scale of a Dyson sphere is almost unimaginable. A sphere with a radius similar to that of Earth’s orbit would have more than a hundred million times the surface area of Earth. Nobody thinks building it would be easy. A single shell is almost certainly out, as it would be under extraordinary stresses and gravitationally unstable. A more plausible option is a swarm: many huge power stations on orbits that do not intersect, effectively surrounding the star. Dyson himself does not like to speculate on the details, or on the likelihood of a sphere being built. “We have no way of judging,” he says. The crucial point is that if any aliens have built Dyson spheres, there is a chance we could spot them.

A sphere would block the sun’s light, making it invisible to our eyes, but the sphere would still emit waste heat in the form of infrared radiation. So, as Carl Sagan pointed out in 1966, if infrared telescopes spot a warm object but nothing shows up at visible wavelengths, it could be a Dyson sphere.

Some natural objects can produce the same effect. Very young and very old stars are often surrounded by dust and gas, which blocks their light and radiates infrared. But the infrared spectrum of these objects should be a giveaway. Silicate minerals in dust produce a distinctive broad peak in the spectrum, and molecules in a warm gas would produce bright or dark spectral lines at specific wavelengths. By contrast, waste heat from a sphere should have a smooth, featureless thermal spectrum. “We would be hoping that the spectrum looks boring,” says Matt Povich at the California State Polytechnic University in Pomona. “The more boring the better.”

Our first good view of the sky at the appropriate wavelengths came when the Infrared Astronomical Satellite surveyed the skies for 10 months in 1983, and a few astronomers have sifted through its data. Vyacheslav Slysh at the Space Research Institute in Moscow made the first attempt in 1985, and Richard Carrigan at Fermilab in Illinois published the latest search in 2009. “I wanted to get into the mode of the British Museum, to go and look for artefacts,” he says.

Carrigan found no persuasive sources, but the range of his search was limited. It would have detected spheres around sunlike stars only within 1000 light years of Earth. This is a very small part of the Milky Way, which is 100,000 light years across.

One reason few have joined Carrigan in the hunt for artefacts is the difficulty of getting funding for such projects. Then last year, the Templeton Foundation – an organisation set up by a billionaire to fund research into the “big questions” – invited proposals for its New Frontiers programme, specifically requesting research that would not normally be funded because of its speculative nature. A few astronomers jumped at the chance to look for alien contraptions and, in October, the programme approved three separate searches. The grants are just a couple of hundred thousand dollars each, but they do not have to fund new telescopes, only new analysis.

One team, led by Jason Wright at Pennsylvania State University in University Park, will look for the waste heat of Dyson spheres by analysing data from two space-based infrared observatories, the Wide-field Infrared Survey Explorer (WISE) and the Spitzer space telescope, launched in 2009 and 2003. Povich, a member of this team, is looking specifically within the Milky Way. Thanks to the data from Spitzer and WISE, Povich should be able to scan a volume of space thousands of times larger than previous searches like Carrigan’s. “For example, if you had a sun-equivalent star, fully enclosed in a Dyson sphere, we should be able to detect it almost anywhere in the galaxy.”

Even such a wide-ranging hunt may not be ambitious enough, according to Wright. He suspects that interstellar travel will prove no harder than constructing a sphere. An alien civilisation with such a high level of technology would spread out and colonise the galaxy in a few million years, building spheres as they go. “I would argue that it’s very hard for a spacefaring civilisation to die out. There are too many lifeboats,” says Wright. “Once you have self-sufficient colonies, you will take over the galaxy – you can’t even try to stop it because you can’t coordinate the actions of the colonies.”

If this had happened in the Milky Way, there should be spheres everywhere. “To find one or a few Dyson spheres in our galaxy would be very strange,” says Wright.

Read the entire article after the jump.

Image: 2001: A Space Odyssey, The Monolith. Courtesy of Daily Galaxy.

BigBang

Shedding Light on Dark Matter

Scientists are cautiously optimistic that results from a particle experiment circling the Earth onboard the International Space Station (ISS) hint at the existence of dark matter.

From Symmetry:

The space-based Alpha Magnetic Spectrometer experiment could be building toward evidence of dark matter, judging by its first result.

The AMS detector does its work more than 200 miles above Earth, latched to the side of the International Space Station. It detects charged cosmic rays, high-energy particles that for the most part originate outside our solar system.

The experiment’s first result, released today, showed an excess of antimatter particles—over the number expected to come from cosmic-ray collisions—in a certain energy range.

There are two competing explanations for this excess. Extra antimatter particles called positrons could be forming in collisions between unseen dark-matter particles and their antiparticles in space. Or an astronomical object such as a pulsar could be firing them into our solar system.

Luckily, there are a couple of ways to find out which explanation is correct.

If dark-matter particles are the culprits, the excess of positrons should sink suddenly above a certain energy. But if a pulsar is responsible, at higher energies the excess will only gradually disappear.

“The way they drop off tells you everything,” said AMS Spokesperson and Nobel laureate Sam Ting, in today’s presentation at CERN, the European center for particle physics.

The AMS result, to be published in Physical Review Letters on April 5, includes data from the energy range between 0.5 and 350 GeV. A graph of the flux of positrons over the flux of electrons and positrons takes the shape of a valley, dipping in the energy range between 0.5 to 10 GeV and then increasing steadily between 10 and 250 GeV. After that point, it begins to dip again—but the graph cuts off just before one can tell whether this is the great drop-off expected in dark matter models or the gradual fade-out expected in pulsar models. This confirms previous results from the PAMELA experiment, with greater precision.

Ting smiled slightly while presenting this cliffhanger, pointing to the empty edge of the graph. “In here, what happens is of great interest,” he said.

“We, of course, have a feeling what is happening,” he said. “But probably it is too early to discuss that.”

Ting kept mum about any data collected so far above that energy, telling curious audience members to wait until the experiment had enough information to present a statistically significant result.

“I’ve been working at CERN for many years. I’ve never made a mistake on an experiment,” he said. “And this is a very difficult experiment.”

A second way to determine the origin of the excess of positrons is to consider where they’re coming from. If positrons are hitting the detector from all directions at random, they could be coming from something as diffuse as dark matter. But if they are arriving from one preferred direction, they might be coming from a pulsar.

So far, the result leans toward the dark-matter explanation, with positrons coming from all directions. But AMS scientists will need to collect more data to say this for certain.

Read the entire article following the jump.

Image: Alpha Magnetic Spectrometer (AMS) detector latched on to the International Space Station. Courtesy of NASA / AMS-02.

BigBang

Mars: 2030

Dennis Tito, the world’s first space tourist, would like to send a private space mission to Mars in 2018. He has pots of money and has founded a non-profit to gather partners and donors to get the mission off the ground. NASA has other plans. The U.S. space agency is tasked by the current administration to plan a human mission to Mars for the mid-2030s. However, due to budgetary issues, fiscal cliffs, and possible debt and deficit reduction, nobody believes it will actually happen. Though, many in NASA and lay-explorers at heart continue to hope.

From Technology Review:

In August, NASA used a series of precise and daring maneuvers to put a one-ton robotic rover named Curiosity on Mars. A capsule containing the rover parachuted through the Martian atmosphere and then unfurled a “sky crane” that lowered Curiosity safely into place. It was a thrilling moment: here were people communicating with a large and sophisticated piece of equipment 150 million miles away as it began to carry out experiments that should enhance our understanding of whether the planet has or has ever had life. So when I visited NASA’s Johnson Space Center in Houston a few days later, I expected to find people still basking in the afterglow. To be sure, the Houston center, where astronauts get directions from Mission Control, didn’t play the leading role in Curiosity. That project was centered at the Jet Propulsion Laboratory, which Caltech manages for NASA in Pasadena. Nonetheless, the landing had been a remarkable event for the entire U.S. space program. And yet I found that Mars wasn’t an entirely happy subject in Houston—especially among people who believe that humans, not only robots, should be exploring there.

In his long but narrow office in the main building of the sprawling Houston center, Bret Drake has compiled an outline explaining how six astronauts could be sent on six-month flights to Mars and what they would do there for a year and a half before their six-month flights home. Drake, 51, has been thinking about this since 1988, when he began working on what he calls the “exploration beyond low Earth orbit dream.” Back then, he expected that people would return to the moon in 2004 and be on the brink of traveling to Mars by now. That prospect soon got ruled out, but Drake pressed on: in the late 1990s he was crafting plans for human Mars missions that could take place around 2018. Today the official goal is for it to happen in the 2030s, but funding cuts have inhibited NASA’s ability to develop many of the technologies that would be required. In fact, progress was halted entirely in 2008 when Congress, in an effort to impose frugality on NASA, prohibited it from using any money to further the human exploration of Mars. “Mars was a four-letter dirty word,” laments Drake, who is deputy chief architect for NASA’s human spaceflight architecture team. Even though that rule was rescinded after a year, Drake knows NASA could perpetually remain 20 years away from a manned Mars mission.

If putting men on the moon signified the extraordinary things that technology made possible in the middle of the 20th century, sending humans to Mars would be the 21st-century version. The flight would be much more arduous and isolating for the astronauts: whereas the Apollo crews who went to the moon were never more than three days from home and could still make out its familiar features, a Mars crew would see Earth shrink into just one of billions of twinkles in space. Once they landed, the astronauts would have to survive in a freezing, windswept world with unbreathable air and 38 percent of Earth’s gravity. But if Drake is right, we can make this journey happen. He and other NASA engineers know what will be required, from a landing vehicle that could get humans through the Martian atmosphere to systems for feeding them, sheltering them, and shuttling them around once they’re there.

The problem facing Drake and other advocates for human exploration of Mars is that the benefits are mostly intangible. Some of the justifications that have been floated—including the idea that people should colonize the planet to improve humanity’s odds of survival—don’t stand up to an economic analysis. Until we have actually tried to keep people alive there, permanent human settlements on Mars will remain a figment of science fiction.

A better argument is that exploring Mars might have scientific benefits, because basic questions about the planet remain unanswered. “We know Mars was once wet and warm,” Drake says. “So did life ever arise there? If so, is it any different than life here on Earth? Where did it all go? What happened to Mars? Why did it become so cold and dry? How can we learn from that and what it may mean for Earth?” But right now Curiosity is exploring these very questions, firing lasers at rocks to determine their composition and hunting for signs of microbial life. Because of such robotic missions, our knowledge of Mars has improved so much in the past 15 years that it’s become harder to make the case for sending humans. People are far more adaptable and ingenious than robots and surely would find things drones can’t, but sending them would jack up the cost of a mission exponentially. “There’s just no real way to justify human exploration solely on the basis of science,” says Cynthia Phillips, a senior research scientist at the SETI Institute, which hunts for evidence of life elsewhere in the universe. “For the cost of sending one human to Mars, you could send an entire flotilla of robots.”

And yet human exploration of Mars has a powerful allure. No planet in our solar system is more like Earth. Our neighbor has rhythms we recognize as our own, with days slightly longer than 24 hours and polar ice caps that grow in the winter and shrink in the summer. Human explorers on Mars would profoundly expand the boundaries of human experience—providing, in the minds of many space advocates, an immeasurable benefit beyond science. “There have always been explorers in our society,” says Phillips. “If space exploration is only robots, you lose something, and you lose something really valuable.”

The Apollo Hangover

Mars was proposed as a place to explore even before the space program existed. In the 1950s, scientists such as Wernher von Braun (who had developed Nazi Germany’s combat rockets and later oversaw work on missiles and rockets for the United States) argued in magazines and on TV that as space became mankind’s next frontier, Mars would be an obvious point of interest. “Will man ever go to Mars?” von Braun wrote in Collier’s magazine in 1954. “I am sure he will—but it will be a century or more before he’s ready.”

Read the entire article after the jump.

Image: Artist’s conception of the Mars Excursion Module (MEM) proposed in a NASA Study in 1964. Courtesy of Dixon, Franklin P. Proceeding of the Symposium on Manned Planetary Missions: 1963/1964, Aeronutronic Divison of Philco Corp.

BigBang

Helplessness and Intelligence Go Hand in Hand

From the Wall Street Journal:

Why are children so, well, so helpless? Why did I spend a recent Sunday morning putting blueberry pancake bits on my 1-year-old grandson’s fork and then picking them up again off the floor? And why are toddlers most helpless when they’re trying to be helpful? Augie’s vigorous efforts to sweep up the pancake detritus with a much-too-large broom (“I clean!”) were adorable but not exactly effective.

This isn’t just a caregiver’s cri de coeur—it’s also an important scientific question. Human babies and young children are an evolutionary paradox. Why must big animals invest so much time and energy just keeping the little ones alive? This is especially true of our human young, helpless and needy for far longer than the young of other primates.

One idea is that our distinctive long childhood helps to develop our equally distinctive intelligence. We have both a much longer childhood and a much larger brain than other primates. Restless humans have to learn about more different physical environments than stay-at-home chimps, and with our propensity for culture, we constantly create new social environments. Childhood gives us a protected time to master new physical and social tools, from a whisk broom to a winning comment, before we have to use them to survive.

The usual museum diorama of our evolutionary origins features brave hunters pursuing a rearing mammoth. But a Pleistocene version of the scene in my kitchen, with ground cassava roots instead of pancakes, might be more accurate, if less exciting.

Of course, many scientists are justifiably skeptical about such “just-so stories” in evolutionary psychology. The idea that our useless babies are really useful learners is appealing, but what kind of evidence could support (or refute) it? There’s still controversy, but two recent studies at least show how we might go about proving the idea empirically.

One of the problems with much evolutionary psychology is that it just concentrates on humans, or sometimes on humans and chimps. To really make an evolutionary argument, you need to study a much wider variety of animals. Is it just a coincidence that we humans have both needy children and big brains? Or will we find the same evolutionary pattern in animals who are very different from us? In 2010, Vera Weisbecker of Cambridge University and a colleague found a correlation between brain size and dependence across 52 different species of marsupials, from familiar ones like kangaroos and opossums to more exotic ones like quokkas.

Quokkas are about the same size as Virginia opossums, but baby quokkas nurse for three times as long, their parents invest more in each baby, and their brains are twice as big.

Read the entire article after the jump.

BigBang

MondayMap: Quiet News Day = Map of the Universe

It was surely a quiet news day on March 21 2013 — most major online news outlets showed a fresh map of the Cosmic Microwave Background (CMB) on the front page. It was taken by the Planck Telescope, operated by the European Space Agency, over a period of 15 months. The image shows a landscape of primordial cosmic microwaves from when the universe was only around 380,000 years old, and is often referred to as “first light”.

From ESA:

Acquired by ESA’s Planck space telescope, the most detailed map ever created of the cosmic microwave background – the relic radiation from the Big Bang – was released today revealing the existence of features that challenge the foundations of our current understanding of the Universe.

The image is based on the initial 15.5 months of data from Planck and is the mission’s first all-sky picture of the oldest light in our Universe, imprinted on the sky when it was just 380 000 years old.

At that time, the young Universe was filled with a hot dense soup of interacting protons, electrons and photons at about 2700ºC. When the protons and electrons joined to form hydrogen atoms, the light was set free. As the Universe has expanded, this light today has been stretched out to microwave wavelengths, equivalent to a temperature of just 2.7 degrees above absolute zero.

This ‘cosmic microwave background’ – CMB – shows tiny temperature fluctuations that correspond to regions of slightly different densities at very early times, representing the seeds of all future structure: the stars and galaxies of today.

According to the standard model of cosmology, the fluctuations arose immediately after the Big Bang and were stretched to cosmologically large scales during a brief period of accelerated expansion known as inflation.

Planck was designed to map these fluctuations across the whole sky with greater resolution and sensitivity than ever before. By analysing the nature and distribution of the seeds in Planck’s CMB image, we can determine the composition and evolution of the Universe from its birth to the present day.

Overall, the information extracted from Planck’s new map provides an excellent confirmation of the standard model of cosmology at an unprecedented accuracy, setting a new benchmark in our manifest of the contents of the Universe.

But because precision of Planck’s map is so high, it also made it possible to reveal some peculiar unexplained features that may well require new physics to be understood.

“The extraordinary quality of Planck’s portrait of the infant Universe allows us to peel back its layers to the very foundations, revealing that our blueprint of the cosmos is far from complete. Such discoveries were made possible by the unique technologies developed for that purpose by European industry,” says Jean-Jacques Dordain, ESA’s Director General.

“Since the release of Planck’s first all-sky image in 2010, we have been carefully extracting and analysing all of the foreground emissions that lie between us and the Universe’s first light, revealing the cosmic microwave background in the greatest detail yet,” adds George Efstathiou of the University of Cambridge, UK.

One of the most surprising findings is that the fluctuations in the CMB temperatures at large angular scales do not match those predicted by the standard model – their signals are not as strong as expected from the smaller scale structure revealed by Planck.

Read the entire article after the jump.

Image: Cosmic microwave background (CMB) seen by Planck. Courtesy of ESA (European Space Agency).

BigBang

Exoplanet Exploration

It wasn’t too long ago that astronomers found the first indirect evidence of a planet beyond our solar system. They inferred the presence of an exoplanet (extrasolar planet) from the periodic dimming or wiggle of its parental star, rather than much more difficult direct observation. Since the first confirmed exoplanet was discovered in 1995 (51 Pegasi b), researchers have definitively  catalogued around 800, and identified another 18,000 candidates. And, the list seems to now grow daily.

If that wasn’t amazing enough researchers now have directly observed several exoplanets and even measured their atmospheric composition.

[div class=attrib]From ars technica:[end-div]

The star system HR 8799 is a sort of Solar System on steroids: a beefier star, four possible planets that are much bigger than Jupiter, and signs of asteroids and cometary bodies, all spread over a bigger region. Additionally, the whole system is younger and hotter, making it one of only a few cases where astronomers can image the planets themselves. However, HR 8799 is very different from our Solar System, as astronomers are realizing thanks to two detailed studies released this week.

The first study was an overview of the four exoplanet candidates, covered by John Timmer. The second set of observations focused on one of the four planet candidates, HR 8799c. Quinn Konopacky, Travis Barman, Bruce Macintosh, and Christian Marois performed a detailed spectral analysis of the atmosphere of the possible exoplanet. They compared their findings to the known properties of a brown dwarf and concluded that they don’t match—it is indeed a young planet. Chemical differences between HR 8799c and its host star led the researchers to conclude the system likely formed in the same way the Solar System did.

The HR 8799 system was one of the first where direct imaging of the exoplanets was possible; in most cases, the evidence for a planet’s presence is indirect. (See the Ars overview of exoplanet science for more.) This serendipity is possible for two major reasons: the system is very young, and the planet candidates orbit far from their host star.

The young age means the bodies orbiting the system still retain heat from their formation and so are glowing in the infrared; older planets emit much less light. That makes it possible to image these planets at these wavelengths. (We mostly image planets in the Solar System using reflected sunlight, but that’s not a viable detection strategy at these distances). A large planet-star separation means that the star’s light doesn’t overwhelm the planets’ warm glow. Astronomers are also assisted by HR 8799’s relative closeness to us—it’s only about 130 light-years away.

However, the brightness of the exoplanet candidates also obscures their identity. They are all much larger than Jupiter—each is more than 5 times Jupiter’s mass, and the largest could be 35 times greater. That, combined with their large infrared emission, could mean that they are not planets but brown dwarfs: star-like objects with insufficient mass to engage in hydrogen fusion. Since brown dwarfs can overlap in size and mass with the largest planets, we haven’t been certain that the objects observed in the HR 8799 system are planets.

For this reason, the two recent studies aimed at measuring the chemistry of these bodies using their spectral emissions. The Palomar study described yesterday provided a broad, big-picture view of the whole HR 8799 system. By contrast, the second study used one of the 10-meter Keck telescopes for a focused, in-depth view of one object: HR 8799c, the second-farthest out of the four.

The researchers measured relatively high levels of carbon monoxide (CO) and water (H2O, just in case you forgot the formula), which were present at levels well above the abundance measured in the spectrum of the host star. According to the researchers, this difference in chemical composition indicated that the planet likely formed via “core accretion”— the gradual, bottom-up accumulation of materials to make a planet—rather than a top-down fragmentation of the disk surrounding the newborn star. The original disk in this scenario would have contained a lot of ice fragments, which merged to make a world relatively high in water content.

In many respects, HR 8799c seemed to have properties between brown dwarfs and other exoplanets, but the chemical and gravitational analyses pushed the object more toward the planet side. In particular, the size and chemistry of HR 8799c placed its surface gravity lower than expected for a brown dwarf, especially when considered with the estimated age of the star system. While this analysis says nothing about whether the other bodies in the system are planets, it does provide further hints about the way the system formed.

One final surprise was the lack of methane (CH4) in HR 8799c’s atmosphere. Methane is a chemical component present in all the Jupiter-like planets in our Solar System. The authors argued that this could be due to vigorous mixing of the atmosphere, which is expected because the exoplanet has higher temperatures and pressures than seen on Jupiter or Neptune. This mixing could enable reactions that limit methane formation. Since the HR 8799 system is much younger than the Solar System—roughly 30 million years compared with 4.5 billion years—it’s uncertain how much this chemical balance may change over time.

[div class=attrib]Read the entire article after the jump.[end-div]

[div class=attrib]One of the discovery images of the system obtained at the Keck II telescope using the adaptive optics system and NIRC2 Near-Infrared Imager. The rectangle indicates the field-of-view of the OSIRIS instrument for planet C. Courtesy of NRC-HIA, C. Marois and Keck Observatory.[end-div]

Arts and Letters, BigBang

Ziggy Stardust and the Spiders from the Moon?

To honor the brilliant new album by the Thin White Duke, we came across the article excerpted below, which at first glance seems to come directly from the songbook of Ziggy Stardust him- or herself. But closer inspection reveals that NASA may have designs on deploying giant manufacturing robots to construct a base on the moon. Can you hear me, Major Tom?

[tube]gH7dMBcg-gE[/tube]

Once you’ve had your fill of Bowie, read on about NASA’s spiders.

[div class=attrib]From ars technica:[end-div]

The first lunar base on the Moon may not be built by human hands, but rather by a giant spider-like robot built by NASA that can bind the dusty soil into giant bubble structures where astronauts can live, conduct experiments, relax or perhaps even cultivate crops.

We’ve already covered the European Space Agency’s (ESA) work with architecture firm Foster + Partners on a proposal for a 3D-printed moonbase, and there are similarities between the two bases—both would be located in Shackleton Crater near the Moon’s south pole, where sunlight (and thus solar energy) is nearly constant due to the Moon’s inclination on the crater’s rim, and both use lunar dust as their basic building material. However, while the ESA’s building would be constructed almost exactly the same way a house would be 3D-printed on Earth, this latest wheeze—SinterHab—uses NASA technology for something a fair bit more ambitious.

The product of joint research first started between space architects Tomas Rousek, Katarina Eriksson and Ondrej Doule and scientists from NASA’s Jet Propulsion Laboratory (JPL), SinterHab is so-named because it involves sintering lunar dust—that is, heating it up to just below its melting point, where the fine nanoparticle powders fuse and become one solid block a bit like a piece of ceramic. To do this, the JPL engineers propose using microwaves no more powerful than those found in a kitchen unit, with tiny particles easily reaching between 1200 and 1500 degrees Celsius.

Nanoparticles of iron within lunar soil are heated at certain microwave frequencies, enabling efficient heating and binding of the dust to itself. Not having to fly binding agent from Earth along with a 3D printer is a major advantage over the ESA/Foster + Partners plan. The solar panels to power the microwaves would, like the moon base itself, be based near or on the rim of Shackleton Crater in near-perpetual sunlight.

“Bubbles” of binded dust could be built by a huge six-legged robot (OK, so it’s not technically a spider) that can then be assembled into habitats large enough for astronauts to use as a base. This “Sinterator system” would use the JPL’s Athlete rover, a half-scale prototype of which has already been built and tested. It’s a human-controlled robotic space rover with wheels at the end of its 8.2m limbs and a detachable habitable capsule mounted at the top.

Athlete’s arms have several different functions, dependent on what it needs to do at any point. It has 48 3D cameras that stream video to its operator either inside the capsule, elsewhere on the Moon or back on Earth, it’s got a payload capacity of 300kg in Earth gravity, and it can scoop, dig, grab at and generally poke around in the soil fairly easily, giving it the combined abilities of a normal rover and a construction vehicle. It can even split into two smaller three-legged rovers at any time if needed. In the Sinterator system, a microwave 3D printer would be mounted on one of the Athlete’s legs and used to build the base.

Rousek explained the background of the idea to Wired.co.uk: “Since many of my buildings have advanced geometry that you can’t cut easily from sheet material, I started using 3D printing for rapid prototyping of my architecture models. The construction industry is still lagging several decades behind car and electronics production. The buildings now are terribly wasteful and imprecise—I have always dreamed about creating a factory where the buildings would be robotically mass-produced with parametric personalization, using composite materials and 3D printing. It would be also great to use local materials and precise manufacturing on-site.”

[div class=attrib]Read the entire article after the jump.[end-div]

[div class=attrib]Image: Giant NASA spider robots could 3D print lunar base using microwaves, courtesy of Wired UK. Video: The Stars (Are Out Tonight), courtesy of David Bowie, ISO Records / Columbia Records.[end-div]